Apoptosis-inducing factor
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='4bur' size='340' side='right' caption='Human apoptosis-inducing factor complex with FAD, NAD and sulfate | + | <StructureSection load='4bur' size='340' side='right' caption='Human apoptosis-inducing factor complex with FAD, NAD and sulfate (PDB code [[4bur]])' scene=''> |
== Function == | == Function == | ||
Revision as of 10:33, 29 December 2016
| |||||||||||
3D structures of apoptosis-inducing factor
Updated on 29-December-2016
4bv6, 4lii, 1m6i – hAIF – human
5fmh, 5kvh, 5kvi, 5fs6, 5fs7, 5fs8, 4fdc – hAIF (mutant)
4bur – hAIF + NAD
3gd3, 1gv4 – mAIF – mouse
3gd4 – mAIF + NAD
References
- ↑ Cande C, Cohen I, Daugas E, Ravagnan L, Larochette N, Zamzami N, Kroemer G. Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria. Biochimie. 2002 Feb-Mar;84(2-3):215-22. PMID:12022952
- ↑ Coughlan MT, Higgins GC, Nguyen TV, Penfold SA, Thallas-Bonke V, Tan SM, Ramm G, Van Bergen NJ, Henstridge DC, Sourris KC, Harcourt BE, Trounce IA, Robb PM, Laskowski A, McGee SL, Genders AJ, Walder K, Drew BG, Gregorevic P, Qian H, Thomas MC, Jerums G, Macisaac RJ, Skene A, Power DA, Ekinci EI, Wijeyeratne XW, Gallo LA, Herman-Edelstein M, Ryan MT, Cooper ME, Thorburn DR, Forbes JM. Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis. Diabetes. 2016 Apr;65(4):1085-98. doi: 10.2337/db15-0864. Epub 2016 Jan 28. PMID:26822084 doi:http://dx.doi.org/10.2337/db15-0864
