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4upc

From Proteopedia

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==Structure of a extracellular domain==
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#REDIRECT [[5a63]] This PDB entry is obsolete and replaced by 5a63
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<StructureSection load='4upc' size='340' side='right' caption='[[4upc]], [[Resolution|resolution]] 5.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4upc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UPC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UPC FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4upc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4upc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4upc RCSB], [http://www.ebi.ac.uk/pdbsum/4upc PDBsum]</span></td></tr>
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<table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/NICA_HUMAN NICA_HUMAN]] Hidradenitis suppurativa. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[[http://www.uniprot.org/uniprot/NICA_HUMAN NICA_HUMAN]] Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
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__TOC__
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</StructureSection>
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[[Category: Bai, X C.]]
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[[Category: Lu, P.]]
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[[Category: Ma, D.]]
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[[Category: Scheres, S H.W.]]
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[[Category: Shi, Y.]]
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[[Category: Sun, L.]]
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[[Category: Xie, T.]]
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[[Category: Yan, C.]]
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[[Category: Yang, G.]]
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[[Category: Zhao, Y.]]
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[[Category: Zhou, R.]]
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[[Category: Protein binding]]
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Current revision

  1. REDIRECT 5a63 This PDB entry is obsolete and replaced by 5a63

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