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5dpx
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==1,2,4-Triazole-3-thione compounds as inhibitors of L1, di-zinc metallo-beta-lactamases.== | |
| - | + | <StructureSection load='5dpx' size='340' side='right' caption='[[5dpx]], [[Resolution|resolution]] 1.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5dpx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DPX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DPX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=L3B:5-(2-METHYLPHENYL)-3H-1,2,4-TRIAZOLE-3-THIONE'>L3B</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fm6|2fm6]], [[2fu7|2fu7]], [[2fu8|2fu8]], [[2fu9|2fu9]], [[2gfj|2gfj]], [[2gfk|2gfk]], [[2hb9|2hb9]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dpx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dpx OCA], [http://pdbe.org/5dpx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dpx RCSB], [http://www.ebi.ac.uk/pdbsum/5dpx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dpx ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BLA1_STEMA BLA1_STEMA]] Has a high activity against imipenem. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Beta-lactamase]] | ||
[[Category: Dideberg, O]] | [[Category: Dideberg, O]] | ||
| + | [[Category: Garau, G]] | ||
[[Category: Khan, R]] | [[Category: Khan, R]] | ||
| - | [[Category: Garau, G]] | ||
[[Category: Nauton, L]] | [[Category: Nauton, L]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Lactamase]] | ||
| + | [[Category: Metallo]] | ||
| + | [[Category: Zn]] | ||
Revision as of 16:24, 18 January 2017
1,2,4-Triazole-3-thione compounds as inhibitors of L1, di-zinc metallo-beta-lactamases.
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Categories: Beta-lactamase | Dideberg, O | Garau, G | Khan, R | Nauton, L | Hydrolase | Lactamase | Metallo | Zn
