This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4r09
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of human TLR8 in complex with ORN06S== | ==Crystal structure of human TLR8 in complex with ORN06S== | ||
<StructureSection load='4r09' size='340' side='right' caption='[[4r09]], [[Resolution|resolution]] 2.62Å' scene=''> | <StructureSection load='4r09' size='340' side='right' caption='[[4r09]], [[Resolution|resolution]] 2.62Å' scene=''> | ||
| Line 5: | Line 6: | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=06S:O-[(2R,3S,4R,5R)-5-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)-2-({[(S)-({(2R,3S,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-HYDROXY-2-[(THIOPHOSPHONOOXY)METHYL]TETRAHYDROFURAN-3-YL}OXY)(SULFANYL)PHOSPHORYL]OXY}METHYL)-4-HYDROXYTETRAHYDROFURAN-3-YL]+DIHYDROGEN+(S)-PHOSPHOROTHIOATE'>06S</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=UPT:1-[(2R,3AR,4R,6R,6AR)-2-HYDROXY-6-(HYDROXYMETHYL)-2-SULFIDOTETRAHYDROFURO[3,4-D][1,3,2]DIOXAPHOSPHOL-4-YL]PYRIMIDINE-2,4(1H,3H)-DIONE'>UPT</scene>, <scene name='pdbligand=URI:URIDINE'>URI</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=06S:O-[(2R,3S,4R,5R)-5-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)-2-({[(S)-({(2R,3S,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-HYDROXY-2-[(THIOPHOSPHONOOXY)METHYL]TETRAHYDROFURAN-3-YL}OXY)(SULFANYL)PHOSPHORYL]OXY}METHYL)-4-HYDROXYTETRAHYDROFURAN-3-YL]+DIHYDROGEN+(S)-PHOSPHOROTHIOATE'>06S</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=UPT:1-[(2R,3AR,4R,6R,6AR)-2-HYDROXY-6-(HYDROXYMETHYL)-2-SULFIDOTETRAHYDROFURO[3,4-D][1,3,2]DIOXAPHOSPHOL-4-YL]PYRIMIDINE-2,4(1H,3H)-DIONE'>UPT</scene>, <scene name='pdbligand=URI:URIDINE'>URI</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r07|4r07]], [[4r08|4r08]], [[4r0a|4r0a]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r07|4r07]], [[4r08|4r08]], [[4r0a|4r0a]]</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r09 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r09 RCSB], [http://www.ebi.ac.uk/pdbsum/4r09 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r09 OCA], [http://pdbe.org/4r09 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r09 RCSB], [http://www.ebi.ac.uk/pdbsum/4r09 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r09 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 17: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4r09" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Toll-like Receptors|Toll-like Receptors]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 17:31, 18 January 2017
Crystal structure of human TLR8 in complex with ORN06S
| |||||||||||
