Elizeu/sandbox/citocromo c

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=== Otitis ===
=== Otitis ===
=== Pneumonia ===
=== Pneumonia ===
 +
PsaA protein is an adhesin which is involved in colonization of the nasopharyngeal mucosal. Moreover, alveolar pneumonia is caused by the spread of ''Streptococcus pneumoniae'' from nasopharynx. Therefore PsaA protein is involved in infection of pulmonary parenchyma by ''Streptococcus pneumoniae''
== Application in Biotechnology ==
== Application in Biotechnology ==

Revision as of 04:24, 25 January 2017

User: Julie Langlois/Sandbox

Contents

Overview

PsaA is a multi-functional lipoprotein detected on all known serotypes of Streptococcus pneumoniae. This lipoprotein belongs to the ABC-type transport protein complex that transports Mn2+. PsaA is also an adhesion factor that plays a major role in pneumococcal attachment to the host cell and virulence.

Image:PsaA dans ABC transporteur.jpg

Structure

PDB ID 3ZK7

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This is 3D structure of PsaA in the metal-free, open state.

PDB ID 3ZTT

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This is 3D structure of PsaA with manganese.

This is a test to add a in the Sandbox

Protein-protein interaction

Function

Disease

Meningitis

Otitis

Pneumonia

PsaA protein is an adhesin which is involved in colonization of the nasopharyngeal mucosal. Moreover, alveolar pneumonia is caused by the spread of Streptococcus pneumoniae from nasopharynx. Therefore PsaA protein is involved in infection of pulmonary parenchyma by Streptococcus pneumoniae

Application in Biotechnology

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