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2jgy
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| - | {{STRUCTURE_2jgy| PDB=2jgy | SCENE= }} | ||
| - | ===THE CRYSTAL STRUCTURE OF HUMAN OROTIDINE-5'-DECARBOXYLASE DOMAIN OF HUMAN URIDINE MONOPHOSPHATE SYNTHETASE (UMPS)=== | ||
| - | == | + | ==The crystal structure of human orotidine-5'-decarboxylase domain of human uridine monophosphate synthetase (UMPS)== |
| - | [[2jgy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <StructureSection load='2jgy' size='340' side='right' caption='[[2jgy]], [[Resolution|resolution]] 1.95Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2jgy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JGY FirstGlance]. <br> | ||
| + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jgy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgy OCA], [http://pdbe.org/2jgy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jgy RCSB], [http://www.ebi.ac.uk/pdbsum/2jgy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jgy ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jg/2jgy_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jgy ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]] | *[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]] | ||
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Orotidine-5'-phosphate decarboxylase]] | [[Category: Orotidine-5'-phosphate decarboxylase]] | ||
| - | [[Category: Arrowsmith, C | + | [[Category: Arrowsmith, C]] |
| - | [[Category: Berg, S | + | [[Category: Berg, S van den]] |
| - | [[Category: Berglund, H | + | [[Category: Berglund, H]] |
| - | [[Category: Busam, R | + | [[Category: Busam, R]] |
| - | [[Category: Collins, R | + | [[Category: Collins, R]] |
| - | [[Category: Dahlgren, L G | + | [[Category: Dahlgren, L G]] |
| - | [[Category: Edwards, A | + | [[Category: Edwards, A]] |
| - | [[Category: Ericsson, U B | + | [[Category: Ericsson, U B]] |
| - | [[Category: Flodin, S | + | [[Category: Flodin, S]] |
| - | [[Category: Flores, A | + | [[Category: Flores, A]] |
| - | [[Category: Graslund, S | + | [[Category: Graslund, S]] |
| - | [[Category: Hallberg, B M | + | [[Category: Hallberg, B M]] |
| - | [[Category: Hammarstrom, M | + | [[Category: Hammarstrom, M]] |
| - | [[Category: Holmberg-Schiavone, L | + | [[Category: Holmberg-Schiavone, L]] |
| - | [[Category: Johansson, I | + | [[Category: Johansson, I]] |
| - | [[Category: Karlberg, T | + | [[Category: Karlberg, T]] |
| - | [[Category: Kosinska, U | + | [[Category: Kosinska, U]] |
| - | [[Category: Kotenyova, T | + | [[Category: Kotenyova, T]] |
| - | [[Category: Lehtio, L | + | [[Category: Lehtio, L]] |
| - | [[Category: Moche, M | + | [[Category: Moche, M]] |
| - | [[Category: Nilsson, M E | + | [[Category: Nilsson, M E]] |
| - | [[Category: Nordlund, P | + | [[Category: Nordlund, P]] |
| - | [[Category: Nyman, T | + | [[Category: Nyman, T]] |
| - | [[Category: Ogg, D | + | [[Category: Ogg, D]] |
| - | [[Category: Persson, C | + | [[Category: Persson, C]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: | + | [[Category: Sagemark, J]] |
| - | [[Category: Stenmark, P | + | [[Category: Stenmark, P]] |
| - | [[Category: Sundstrom, M | + | [[Category: Sundstrom, M]] |
| - | [[Category: Thorsell, A G | + | [[Category: Thorsell, A G]] |
| - | [[Category: Uppenberg, J | + | [[Category: Uppenberg, J]] |
| - | [[Category: Upsten, M | + | [[Category: Upsten, M]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
[[Category: Decarboxylase]] | [[Category: Decarboxylase]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
Current revision
The crystal structure of human orotidine-5'-decarboxylase domain of human uridine monophosphate synthetase (UMPS)
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Categories: Human | Orotidine-5'-phosphate decarboxylase | Arrowsmith, C | Berg, S van den | Berglund, H | Busam, R | Collins, R | Dahlgren, L G | Edwards, A | Ericsson, U B | Flodin, S | Flores, A | Graslund, S | Hallberg, B M | Hammarstrom, M | Holmberg-Schiavone, L | Johansson, I | Karlberg, T | Kosinska, U | Kotenyova, T | Lehtio, L | Moche, M | Nilsson, M E | Nordlund, P | Nyman, T | Ogg, D | Persson, C | Structural genomic | Sagemark, J | Stenmark, P | Sundstrom, M | Thorsell, A G | Uppenberg, J | Upsten, M | Weigelt, J | Decarboxylase | Disease mutation | Glycosyltransferase | Lyase | Multifunctional enzyme | Orotidine-5'-decarboxylase | Pyrimidine biosynthesis | Tim barrel dimer | Transferase
