Mutations in BRCA1/BARD1 RING-domain heterodimer
From Proteopedia
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==Benign mutations== | ==Benign mutations== | ||
| - | *<scene name='75/751104/Cv/ | + | *'''Mutation K45Q:''' <scene name='75/751104/Cv/26'>Wild type</scene> and the <jmol><jmolButton><script>frame next</script><text>Mutation</text></jmolButton></jmol>. <scene name='75/751104/Cv/24'>Mutated and wildtype residues together</scene>. <scene name='75/751104/Cv/25'>Click here to see animation of this scene</scene>. |
*<scene name='75/751104/Cv/11'>Mutation D67Y</scene>. <jmol><jmolButton><script>frame 1</script><text>Wild type</text></jmolButton></jmol> and the <jmol><jmolButton><script>frame next</script><text>Mutation</text></jmolButton></jmol>. <scene name='75/751104/Cv/10'>Click here to see animation of this scene</scene>. | *<scene name='75/751104/Cv/11'>Mutation D67Y</scene>. <jmol><jmolButton><script>frame 1</script><text>Wild type</text></jmolButton></jmol> and the <jmol><jmolButton><script>frame next</script><text>Mutation</text></jmolButton></jmol>. <scene name='75/751104/Cv/10'>Click here to see animation of this scene</scene>. | ||
</StructureSection> | </StructureSection> | ||
Revision as of 08:53, 5 February 2017
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References
- ↑ Brzovic PS, Rajagopal P, Hoyt DW, King MC, Klevit RE. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat Struct Biol. 2001 Oct;8(10):833-7. PMID:11573085 doi:10.1038/nsb1001-833
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Alexander Berchansky, Michal Harel, Jaime Prilusky, Joel L. Sussman
