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==Interactions== | ==Interactions== | ||
| - | The zinc-fingers usually interact with the outside of B-DNA. When interacting with DNA, the zinc fingers bind in the major groove of B-DNA and wrap part way around the double helix. | + | The zinc-fingers usually interact with the outside of B-DNA. When interacting with DNA, the zinc fingers bind in the major groove of B-DNA and wrap part way around the double helix, following a right-handed helical path. |
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==Work Cited== | ==Work Cited== | ||
Zinc Fingers. (n.d.). Retrieved February 08, 2017, from http://www.ebi.ac.uk/interpro/potm/2007_3/Page2.htm | Zinc Fingers. (n.d.). Retrieved February 08, 2017, from http://www.ebi.ac.uk/interpro/potm/2007_3/Page2.htm | ||
Revision as of 20:26, 8 February 2017
Contents |
Zinc-finger 1
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Function
Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation. regulate eukaryotic gene expression
Interactions
The zinc-fingers usually interact with the outside of B-DNA. When interacting with DNA, the zinc fingers bind in the major groove of B-DNA and wrap part way around the double helix, following a right-handed helical path.
Work Cited
Zinc Fingers. (n.d.). Retrieved February 08, 2017, from http://www.ebi.ac.uk/interpro/potm/2007_3/Page2.htm
