Mutations in BRCA1/BARD1 RING-domain heterodimer
From Proteopedia
(Difference between revisions)
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| - | animation on; animation mode loop; frame 1 1 play; animation off; frame 1; | + | animation on; animation mode loop; frame 1 1 play; animation off; frame 1; select [LEU]22;color selectionHalos green;selectionHalos on; |
</script> | </script> | ||
<text>Wild type conformation,</text> | <text>Wild type conformation,</text> | ||
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<script> | <script> | ||
| - | animation on; animation mode loop; frame 2 2 play; animation off; frame 2; | + | animation on; animation mode loop; frame 2 2 play; animation off; frame 2; select [SER]22;color selectionHalos red;selectionHalos on; |
</script> | </script> | ||
<text>Mutation | <text>Mutation | ||
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| - | animation off; frame all | + | animation off; frame all; select [LEU]22;color selectionHalos green;selectionHalos on; select [SER]22;color selectionHalos red;selectionHalos on; |
</script> | </script> | ||
<text>Mutated and wildtype residues | <text>Mutated and wildtype residues | ||
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<jmolLink> | <jmolLink> | ||
<script> | <script> | ||
| - | animation on; animation mode loop; frame play | + | animation on; animation mode loop; frame play; select [LEU]22;color selectionHalos green;selectionHalos on; select [SER]22;color selectionHalos red;selectionHalos on; |
</script> | </script> | ||
<text>see animation | <text>see animation | ||
Revision as of 11:54, 15 February 2017
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References
- ↑ Brzovic PS, Rajagopal P, Hoyt DW, King MC, Klevit RE. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat Struct Biol. 2001 Oct;8(10):833-7. PMID:11573085 doi:10.1038/nsb1001-833
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Alexander Berchansky, Michal Harel, Jaime Prilusky, Joel L. Sussman
