5szx
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Epstein-Barr virus Zta DNA binding domain homodimer in complex with methylated DNA== | |
| - | + | <StructureSection load='5szx' size='340' side='right' caption='[[5szx]], [[Resolution|resolution]] 2.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5szx]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SZX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5SZX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5t01|5t01]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5szx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5szx OCA], [http://pdbe.org/5szx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5szx RCSB], [http://www.ebi.ac.uk/pdbsum/5szx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5szx ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BZLF1_EBVB9 BZLF1_EBVB9]] Plays a key role in the switch from latent infection to lytic cycle producing new virions. Acts as a transcription factor, inducing early lytic cycle genes, and as a origin binding protein for genome replication. BZLF1 activates the promoter of another EBV gene (BSLF2+BMLF1).<ref>PMID:2157874</ref> <ref>PMID:1847997</ref> <ref>PMID:8404860</ref> <ref>PMID:17079287</ref> <ref>PMID:19144704</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Cheng, X]] | ||
| + | [[Category: Hong, S]] | ||
| + | [[Category: Horton, J R]] | ||
| + | [[Category: 5-methylcytosine]] | ||
| + | [[Category: Ap-1]] | ||
| + | [[Category: Basic leucine-zipper]] | ||
| + | [[Category: Bzip]] | ||
| + | [[Category: Bzlf-1]] | ||
| + | [[Category: Dna methylation]] | ||
| + | [[Category: Ebv]] | ||
| + | [[Category: Epstein-barr virus]] | ||
| + | [[Category: Transcription factor]] | ||
| + | [[Category: Transcription regulator-dna complex]] | ||
| + | [[Category: Zebra]] | ||
| + | [[Category: Zta]] | ||
Revision as of 09:39, 11 March 2017
Epstein-Barr virus Zta DNA binding domain homodimer in complex with methylated DNA
| |||||||||||
