CD44

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[[2jcp]] - mCD44 hyaluronan-binding domain – mouse<br />
[[2jcp]] - mCD44 hyaluronan-binding domain – mouse<br />
[[2jcq]], [[2jcr]] - mCD44 hyaluronan-binding domain + 8-mer HA<br />
[[2jcq]], [[2jcr]] - mCD44 hyaluronan-binding domain + 8-mer HA<br />
-
[[4mrd]], [[4mre]], [[4mrf]], [[4mrg]], [[4mrh]], [[4np2]], [[4np3]] - mCD44 hyaluronan-binding domain + inhibitor<br />
+
[[4mrd]], [[4mre]], [[4mrf]], [[4mrg]], [[4mrh]], [[4np2]], [[4bzc]], [[4bzk]] - mCD44 hyaluronan-binding domain + inhibitor<br />
 +
[[5bzt]], [[5bzs]], [[5bzr]], [[5bzq]], [[5bzp]], [[5bzo]], [[5bzn]], [[5bzm]], [[5bzl]], [[5bzj]], [[5bzi]], [[5bzh]], [[5bzg]], [[5bzf]], [[5bze]] - mCD44 hyaluronan-binding domain (mutant) + inhibitor<br />
[[4np3]] - mCD44 hyaluronan-binding domain + tetrapeptide<br />
[[4np3]] - mCD44 hyaluronan-binding domain + tetrapeptide<br />
 +
[[4pz3]] - hCD44 hyaluronan-binding domain + tetrapeptide<br /`>
 +
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:35, 29 March 2017

Structure of mouse CD44 hyaluronan-binding domain complex with hyaluronic acid (PDB code 2jca)

Drag the structure with the mouse to rotate

Contents

3D structures of CD44

Updated on 29-March-2017

1uuh, 4pz4 – hCD44 hyaluronan-binding domain – human
1poz, 2i83 - hCD44 hyaluronan-binding domain – NMR
2jcp - mCD44 hyaluronan-binding domain – mouse
2jcq, 2jcr - mCD44 hyaluronan-binding domain + 8-mer HA
4mrd, 4mre, 4mrf, 4mrg, 4mrh, 4np2, 4bzc, 4bzk - mCD44 hyaluronan-binding domain + inhibitor
5bzt, 5bzs, 5bzr, 5bzq, 5bzp, 5bzo, 5bzn, 5bzm, 5bzl, 5bzj, 5bzi, 5bzh, 5bzg, 5bzf, 5bze - mCD44 hyaluronan-binding domain (mutant) + inhibitor
4np3 - mCD44 hyaluronan-binding domain + tetrapeptide
4pz3 - hCD44 hyaluronan-binding domain + tetrapeptide

References

  1. ↑ Liu LK, Finzel B. High-resolution crystal structures of alternate forms of the human CD44 hyaluronan-binding domain reveal a site for protein interaction. Acta Crystallogr F Struct Biol Commun. 2014 Sep 1;70(Pt 9):1155-61. doi:, 10.1107/S2053230X14015532. Epub 2014 Aug 29. PMID:25195884 doi:http://dx.doi.org/10.1107/S2053230X14015532
  2. ↑ Banerji S, Wright AJ, Noble M, Mahoney DJ, Campbell ID, Day AJ, Jackson DG. Structures of the Cd44-hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction. Nat Struct Mol Biol. 2007 Mar;14(3):234-9. Epub 2007 Feb 11. PMID:17293874 doi:10.1038/nsmb1201

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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