TRNA-guanine transglycosylase
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
| - | TGT overall structure is of a <scene name='55/551184/Cv/2'>Tim barrel</scene>. A structural <scene name='55/551184/Cv/3'>Zn+2 ion is tetrahedrally coordinated</scene> in the C-terminal subdomain. The active site contains | + | TGT overall structure is of a <scene name='55/551184/Cv/2'>Tim barrel</scene>. A structural <scene name='55/551184/Cv/3'>Zn+2 ion is tetrahedrally coordinated</scene> in the C-terminal subdomain. The <scene name='55/551184/Cv/4'>active site contains queuine precursor</scene><ref>PMID:14523925</ref>. |
</StructureSection> | </StructureSection> | ||
Revision as of 11:51, 6 April 2017
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3D structures of tRNA-guanine transglycosylase
Updated on 06-April-2017
References
- ↑ Nonekowski ST, Garcia GA. tRNA recognition by tRNA-guanine transglycosylase from Escherichia coli: the role of U33 in U-G-U sequence recognition. RNA. 2001 Oct;7(10):1432-41. PMID:11680848
- ↑ Sabina J, Soll D. The RNA-binding PUA domain of archaeal tRNA-guanine transglycosylase is not required for archaeosine formation. J Biol Chem. 2006 Mar 17;281(11):6993-7001. Epub 2006 Jan 10. PMID:16407303 doi:http://dx.doi.org/M512841200
- ↑ Brenk R, Stubbs MT, Heine A, Reuter K, Klebe G. Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug design. Chembiochem. 2003 Oct 6;4(10):1066-77. PMID:14523925 doi:10.1002/cbic.200300644
