5hgj
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of integrin alpha1beta1 and alpha2beta1 I-domains explain differential calcium-mediated ligand recognition== | |
| - | + | <StructureSection load='5hgj' size='340' side='right' caption='[[5hgj]], [[Resolution|resolution]] 1.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5hgj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HGJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HGJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hgj OCA], [http://pdbe.org/5hgj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hgj RCSB], [http://www.ebi.ac.uk/pdbsum/5hgj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hgj ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ITA1_HUMAN ITA1_HUMAN]] Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Abe, H]] | ||
| + | [[Category: Banerjee, S]] | ||
| + | [[Category: Blackwell, T]] | ||
| + | [[Category: Brown, K L]] | ||
| + | [[Category: Feigley, A]] | ||
| + | [[Category: Hudson, B H]] | ||
| + | [[Category: Pozzi, A]] | ||
| + | [[Category: Zent, R]] | ||
| + | [[Category: Cell adhesion]] | ||
| + | [[Category: I-domain]] | ||
| + | [[Category: Integrin]] | ||
| + | [[Category: Rossman]] | ||
| + | [[Category: Signaling]] | ||
Revision as of 11:41, 12 April 2017
Structure of integrin alpha1beta1 and alpha2beta1 I-domains explain differential calcium-mediated ligand recognition
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Categories: Abe, H | Banerjee, S | Blackwell, T | Brown, K L | Feigley, A | Hudson, B H | Pozzi, A | Zent, R | Cell adhesion | I-domain | Integrin | Rossman | Signaling
