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5v8w
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human Integrator IntS9-IntS11 CTD complex== | |
| - | + | <StructureSection load='5v8w' size='340' side='right' caption='[[5v8w]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5v8w]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V8W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V8W FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v8w OCA], [http://pdbe.org/5v8w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v8w RCSB], [http://www.ebi.ac.uk/pdbsum/5v8w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v8w ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/INT9_HUMAN INT9_HUMAN]] Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. [[http://www.uniprot.org/uniprot/INT11_HUMAN INT11_HUMAN]] Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage.<ref>PMID:16239144</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Tong, L]] | ||
| + | [[Category: Wu, Y]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Integrator complex]] | ||
| + | [[Category: Snrna processing]] | ||
Revision as of 11:49, 12 April 2017
Crystal structure of human Integrator IntS9-IntS11 CTD complex
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