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==Crystal Structures of mPGES-1 Inhibitor Complexes==
==Crystal Structures of mPGES-1 Inhibitor Complexes==
<StructureSection load='4yk5' size='340' side='right' caption='[[4yk5]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
<StructureSection load='4yk5' size='340' side='right' caption='[[4yk5]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4DV:3-[1-(4-CHLOROBENZYL)-5-(2-FLUORO-2-METHYLBIPHENYL-4-YL)-3-METHYL-1H-INDOL-2-YL]-2,2-DIMETHYLPROPANOIC+ACID'>4DV</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=JZR:HEXYL+BETA-D-GLUCOPYRANOSIDE'>JZR</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4DV:3-[1-(4-CHLOROBENZYL)-5-(2-FLUORO-2-METHYLBIPHENYL-4-YL)-3-METHYL-1H-INDOL-2-YL]-2,2-DIMETHYLPROPANOIC+ACID'>4DV</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=JZR:HEXYL+BETA-D-GLUCOPYRANOSIDE'>JZR</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yk5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yk5 RCSB], [http://www.ebi.ac.uk/pdbsum/4yk5 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yk5 OCA], [http://pdbe.org/4yk5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yk5 RCSB], [http://www.ebi.ac.uk/pdbsum/4yk5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yk5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4yk5" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>

Revision as of 13:31, 19 April 2017

Crystal Structures of mPGES-1 Inhibitor Complexes

4yk5, resolution 1.42Å

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