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DNA methyltransferase
From Proteopedia
(Difference between revisions)
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**[[2uyc]], [[2uyh]], [[2uz4]] - Hh-cytosine DNMT (mutant) + DNA + SAH | **[[2uyc]], [[2uyh]], [[2uz4]] - Hh-cytosine DNMT (mutant) + DNA + SAH | ||
| - | **[[3a1b]] - h-cytosine DNMT ADD domain + histone H3 | + | **[[3a1b]], [[4qbq]] - h-cytosine DNMT ADD domain + histone H3<br /> |
| + | **[[4qbr]], [[4qbs]] - h-cytosine DNMT ADD domain (mutant) + histone H3<br /> | ||
| + | **[[5ciu]] - h-cytosine DNMT residues 206-355 + histone H3.2<br /> | ||
| + | **[[4yoc]] - h-cytosine DNMT residues 600-1600 + ubiquitin carboxyl-terminal hydrolase 7<br /> | ||
| + | **[[4wxx]] - h-cytosine DNMT residues 351-1600 + SAH<br /> | ||
| + | **[[4u7p]] - h-cytosine DNMT 3A residues 455-912 + h-cytosine DNMT 3-like residues 178-379 + SAH<br /> | ||
| + | **[[4u7t]] - h-cytosine DNMT 3A residues 455-912 + h-cytosine DNMT 3-like residues 178-379 + histone 3.3 + SAH<br /> | ||
**[[3pt6]], [[3pt9]], [[4da4]] – m-cytosine DNMT + DNA | **[[3pt6]], [[3pt9]], [[4da4]] – m-cytosine DNMT + DNA | ||
| Line 99: | Line 105: | ||
**[[1nw6]] - RsN6-adenine DNMT + sinefungin<br /> | **[[1nw6]] - RsN6-adenine DNMT + sinefungin<br /> | ||
**[[1nw7]] - RsN6-adenine DNMT + SAH<br /> | **[[1nw7]] - RsN6-adenine DNMT + SAH<br /> | ||
| - | **[[1nw8]] - RsN6-adenine DNMT (mutant) | + | **[[1nw8]] - RsN6-adenine DNMT (mutant)<br /> |
| + | **[[5hek]] - HpN6-adenine DNMT – ''Helicobacter pylori''<br /> | ||
| + | **[[5hfj]] - HpN6-adenine DNMT + SAM<br /> | ||
**[[2ibs]], [[2ibt]], [[2ih2]], [[2ih4]], [[2ih5]], [[2np6]], [[2np7]], [[1g38]] - Ta-adenine DNMT Taqi + DNA + cofactor analog – ''Thermus aquaticus''<br /> | **[[2ibs]], [[2ibt]], [[2ih2]], [[2ih4]], [[2ih5]], [[2np6]], [[2np7]], [[1g38]] - Ta-adenine DNMT Taqi + DNA + cofactor analog – ''Thermus aquaticus''<br /> | ||
**[[1aqi]] – Ta-adenine DNMT Taqi + SAH<br /> | **[[1aqi]] – Ta-adenine DNMT Taqi + SAH<br /> | ||
| - | **[[1aqj]] – Ta-adenine DNMT Taqi + | + | **[[1aqj]] – Ta-adenine DNMT Taqi + sinefungin<br /> |
**[[2adm]] - Ta-adenine DNMT Taqi + SAM<br /> | **[[2adm]] - Ta-adenine DNMT Taqi + SAM<br /> | ||
| - | **[[1g60]] - adenine DNMT + SAM – ''Moraxella bovis'' | + | **[[1g60]] - adenine DNMT + SAM – ''Moraxella bovis''<br /> |
| + | **[[4rtj]], [[4rtl]], [[4rto]] - Ec-adenine DNMT + DNA + sinefungin<br /> | ||
| + | **[[4rtk]] - Ec-adenine DNMT + DNA + SAH<br /> | ||
| + | **[[4gbe]] - Ec-adenine DNMT + SAH<br /> | ||
| + | **[[4gol]], [[4gom]], [[4gon]], [[4goo]] - Ec-adenine DNMT + SAM derivative<br /> | ||
| + | **[[4rtm]], [[4rtp]], [[4rtr]], [[4rts]] - Ec-adenine DNMT + DNA + AdoMet<br /> | ||
| + | **[[4rtn]], [[4rtq]] - Ec-adenine DNMT + DNA + AdoHcy<br /> | ||
*HhaI DNA methyltransferase | *HhaI DNA methyltransferase | ||
| Line 122: | Line 136: | ||
**[[2z6q]] – HhHDMT (mutant) + DNA + SAH + deoxycytidine <BR /> | **[[2z6q]] – HhHDMT (mutant) + DNA + SAH + deoxycytidine <BR /> | ||
**[[2uyc]], [[2uyh]], [[2uz4]] – HhHDMT (mutant) + DNA + SAH + methyl cytosine <BR /> | **[[2uyc]], [[2uyh]], [[2uz4]] – HhHDMT (mutant) + DNA + SAH + methyl cytosine <BR /> | ||
| + | |||
| + | *DNA methyltransferase | ||
| + | |||
| + | **[[4onj]] – tHDMT catalytic domain + sinefungin – tobacco <BR /> | ||
| + | **[[4onq]] – tHDMT catalytic domain (mutant) + sinefungin <BR /> | ||
}} | }} | ||
Revision as of 10:24, 24 April 2017
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3D Structures of DNA methyltransferase
Updated on 24-April-2017
References
- ↑ Kaina B, Christmann M, Naumann S, Roos WP. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents. DNA Repair (Amst). 2007 Aug 1;6(8):1079-99. Epub 2007 May 7. PMID:17485253 doi:http://dx.doi.org/10.1016/j.dnarep.2007.03.008
- ↑ Kumar S, Cheng X, Klimasauskas S, Mi S, Posfai J, Roberts RJ, Wilson GG. The DNA (cytosine-5) methyltransferases. Nucleic Acids Res. 1994 Jan 11;22(1):1-10. PMID:8127644
- ↑ Thomas CB, Scavetta RD, Gumport RI, Churchill ME. Structures of liganded and unliganded RsrI N6-adenine DNA methyltransferase: a distinct orientation for active cofactor binding. J Biol Chem. 2003 Jul 11;278(28):26094-101. Epub 2003 May 4. PMID:12732637 doi:http://dx.doi.org/10.1074/jbc.M303751200
- ↑ Sankpal UT, Rao DN. Structure, function, and mechanism of HhaI DNA methyltransferases. Crit Rev Biochem Mol Biol. 2002;37(3):167-97. PMID:12139442 doi:http://dx.doi.org/10.1080/10409230290771492
