1v0m
From Proteopedia
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|PDB= 1v0m |SIZE=350|CAPTION= <scene name='initialview01'>1v0m</scene>, resolution 1.07Å | |PDB= 1v0m |SIZE=350|CAPTION= <scene name='initialview01'>1v0m</scene>, resolution 1.07Å | ||
|SITE= <scene name='pdbsite=ACB:Imd+Binding+Site+For+Chain+A'>ACB</scene> | |SITE= <scene name='pdbsite=ACB:Imd+Binding+Site+For+Chain+A'>ACB</scene> | ||
| - | |LIGAND= <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene> | + | |LIGAND= <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=XDN:PIPERIDINE-3,4,5-TRIOL'>XDN</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene> |
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span> |
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v0m OCA], [http://www.ebi.ac.uk/pdbsum/1v0m PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1v0m RCSB]</span> | ||
}} | }} | ||
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[[Category: Williams, S J.]] | [[Category: Williams, S J.]] | ||
[[Category: Withers, S G.]] | [[Category: Withers, S G.]] | ||
| - | [[Category: IMD]] | ||
[[Category: deoxynojirimycin]] | [[Category: deoxynojirimycin]] | ||
[[Category: glycoside hydrolase family 10]] | [[Category: glycoside hydrolase family 10]] | ||
| Line 37: | Line 39: | ||
[[Category: xylanase]] | [[Category: xylanase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:17:58 2008'' |
Revision as of 21:17, 30 March 2008
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| , resolution 1.07Å | |||||||
|---|---|---|---|---|---|---|---|
| Sites: | |||||||
| Ligands: | , , | ||||||
| Activity: | Endo-1,4-beta-xylanase, with EC number 3.2.1.8 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
XYLANASE XYN10A FROM STREPTOMYCES LIVIDANS IN COMPLEX WITH XYLOBIO-DEOXYNOJIRIMYCIN AT PH 7.5
Overview
The atomic resolution structures of xylobiose-derived isofagomine and xylobiose-derived deoxynojirimycin in complex with the xylanase Xyn10A from Streptomyces lividans reveal undistorted (4)C(1) chair conformed sugars and, in the case of the deoxynojirimycin analogue, suggest unusual pK(a) changes of the enzyme's catalytic machinery upon binding.
About this Structure
1V0M is a Single protein structure of sequence from Streptomyces lividans. Full crystallographic information is available from OCA.
Reference
Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A., Gloster TM, Williams SJ, Roberts S, Tarling CA, Wicki J, Withers SG, Davies GJ, Chem Commun (Camb). 2004 Aug 21;(16):1794-5. Epub 2004 Jul 23. PMID:15306887
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