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5jm4

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'''Unreleased structure'''
 
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The entry 5jm4 is ON HOLD until Paper Publication
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==Crystal structure of 14-3-3zeta in complex with a cyclic peptide involving an adamantyl and a dicarboxy side chain==
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<StructureSection load='5jm4' size='340' side='right' caption='[[5jm4]], [[Resolution|resolution]] 2.34&Aring;' scene=''>
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Authors: Bier, D., Krueger, D., Glas, A., Wallraven, K., Ottmann, C., Hennig, S., Grossmann, T.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5jm4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JM4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JM4 FirstGlance]. <br>
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Description: Crystal structure of 14-3-3zeta in complex with a cyclic peptide involving an adamantyl and a dicarboxy side chain
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=6L9:[(2S)-2,3-DIAMINO-3-OXOPROPYL]PROPANEDIOIC+ACID'>6L9</scene>, <scene name='pdbligand=A1G:(2S)-AMINO[(3R,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DECAN-1-YL]ACETIC+ACID'>A1G</scene>, <scene name='pdbligand=MKD:(2S)-2-AMINO-2-METHYLOCTANOIC+ACID'>MKD</scene></td></tr>
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[[Category: Wallraven, K]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4n7g|4n7g]], [[4n84|4n84]]</td></tr>
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[[Category: Hennig, S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jm4 OCA], [http://pdbe.org/5jm4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jm4 RCSB], [http://www.ebi.ac.uk/pdbsum/5jm4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jm4 ProSAT]</span></td></tr>
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[[Category: Ottmann, C]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/1433Z_HUMAN 1433Z_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.<ref>PMID:9360956</ref> <ref>PMID:14578935</ref> <ref>PMID:15071501</ref> <ref>PMID:15644438</ref> <ref>PMID:16376338</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bier, D]]
[[Category: Bier, D]]
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[[Category: Glas, A]]
[[Category: Grossmann, T]]
[[Category: Grossmann, T]]
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[[Category: Hennig, S]]
[[Category: Krueger, D]]
[[Category: Krueger, D]]
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[[Category: Glas, A]]
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[[Category: Ottmann, C]]
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[[Category: Wallraven, K]]
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[[Category: Macrocycle]]
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[[Category: Peptidomimetic]]
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[[Category: Ppi inhibitor]]
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[[Category: Signaling protein]]

Revision as of 12:56, 10 May 2017

Crystal structure of 14-3-3zeta in complex with a cyclic peptide involving an adamantyl and a dicarboxy side chain

5jm4, resolution 2.34Å

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