5kbz
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the PksA Product Template domain in complex with a phosphopantetheine mimetic== | |
| - | + | <StructureSection load='5kbz' size='340' side='right' caption='[[5kbz]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5kbz]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KBZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KBZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3B2:(14R)-14-HYDROXY-15,15-DIMETHYL-1-[5-({[(5-METHYL-1,2-OXAZOL-3-YL)METHYL]SULFANYL}METHYL)-1,2-OXAZOL-3-YL]-4,9,13-TRIOXO-2-THIA-5,8,12-TRIAZAHEXADECAN-16-YL+DIHYDROGEN+PHOSPHATE'>3B2</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hrr|3hrr]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Noranthrone_synthase Noranthrone synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.221 2.3.1.221] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kbz OCA], [http://pdbe.org/5kbz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kbz RCSB], [http://www.ebi.ac.uk/pdbsum/5kbz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kbz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PKSL1_ASPPA PKSL1_ASPPA]] Combines a hexanoyl starter unit and 7 malonyl-CoA extender units to synthesize the precursor norsolorinic acid anthrone (noranthrone) in the aflatoxin biosynthesis pathway. The hexanoyl starter unit is provided to the acyl-carrier protein (ACP) domain by a dedicated fungal fatty acid synthase.<ref>PMID:15006741</ref> <ref>PMID:18403714</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Noranthrone synthase]] | ||
| + | [[Category: Barajas, J F]] | ||
| + | [[Category: Burkart, M D]] | ||
| + | [[Category: Clair, J J.La]] | ||
| + | [[Category: Jackson, D R]] | ||
| + | [[Category: Moreno, G]] | ||
| + | [[Category: Rivera, H]] | ||
| + | [[Category: Shakya, G]] | ||
| + | [[Category: Topper, C L]] | ||
| + | [[Category: Townsend, C A]] | ||
| + | [[Category: Tsai, S C]] | ||
| + | [[Category: Vagstad, A]] | ||
| + | [[Category: Aflatoxin]] | ||
| + | [[Category: Cyclase]] | ||
| + | [[Category: Dehydratase]] | ||
| + | [[Category: Double hot dog fold]] | ||
| + | [[Category: Polyketide]] | ||
| + | [[Category: Polyketide synthase]] | ||
| + | [[Category: Product template]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 12:57, 10 May 2017
Structure of the PksA Product Template domain in complex with a phosphopantetheine mimetic
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Categories: Noranthrone synthase | Barajas, J F | Burkart, M D | Clair, J J.La | Jackson, D R | Moreno, G | Rivera, H | Shakya, G | Topper, C L | Townsend, C A | Tsai, S C | Vagstad, A | Aflatoxin | Cyclase | Dehydratase | Double hot dog fold | Polyketide | Polyketide synthase | Product template | Transcription
