1vgn

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|PDB= 1vgn |SIZE=350|CAPTION= <scene name='initialview01'>1vgn</scene>, resolution 2.63&Aring;
|PDB= 1vgn |SIZE=350|CAPTION= <scene name='initialview01'>1vgn</scene>, resolution 2.63&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=OPS:3-OXO-3-[(3-OXOPROPYL)SULFANYL]PROPANE-1-THIOLATE'>OPS</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene>
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|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=OPS:3-OXO-3-[(3-OXOPROPYL)SULFANYL]PROPANE-1-THIOLATE'>OPS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span>
|GENE=
|GENE=
 +
|DOMAIN=
 +
|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vgn OCA], [http://www.ebi.ac.uk/pdbsum/1vgn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1vgn RCSB]</span>
}}
}}
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[[Category: Yamagata, Y.]]
[[Category: Yamagata, Y.]]
[[Category: Yamaguchi, Y.]]
[[Category: Yamaguchi, Y.]]
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[[Category: ACY]]
 
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[[Category: OPS]]
 
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[[Category: ZN]]
 
[[Category: irreversible inhibitor]]
[[Category: irreversible inhibitor]]
[[Category: metallo-beta-lactamase]]
[[Category: metallo-beta-lactamase]]
[[Category: zinc]]
[[Category: zinc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:45:18 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:24:12 2008''

Revision as of 21:24, 30 March 2008


PDB ID 1vgn

Drag the structure with the mouse to rotate
, resolution 2.63Å
Ligands: , ,
Activity: Beta-lactamase, with EC number 3.5.2.6
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Structure-based design of the irreversible inhibitors to metallo--lactamase (IMP-1)


About this Structure

1VGN is a Single protein structure of sequence from Serratia marcescens. Full crystallographic information is available from OCA.

Reference

Irreversible inhibition of metallo-beta-lactamase (IMP-1) by 3-(3-mercaptopropionylsulfanyl)propionic acid pentafluorophenyl ester., Kurosaki H, Yamaguchi Y, Higashi T, Soga K, Matsueda S, Yumoto H, Misumi S, Yamagata Y, Arakawa Y, Goto M, Angew Chem Int Ed Engl. 2005 Jun 20;44(25):3861-4. PMID:15892033

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