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Severin
From Proteopedia
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| + | <StructureSection load='1svy' size='350' side='right' scene='' caption='Severin domain 2 complex with Ca+2 (green) and Na+ (purple) ions [[1svy]]'> | ||
[[Image:Severin.png|left|200px|thumb|Crystal Structure of Human Severin, [[3fg6]]]] | [[Image:Severin.png|left|200px|thumb|Crystal Structure of Human Severin, [[3fg6]]]] | ||
| - | {{STRUCTURE_1svy| PDB=1svy | SCENE= |CAPTION=Severin domain 2 complex with Ca+2 (green) and Na+ (purple) ions [[1svy]] }} | ||
[[Severin]] is a calcium-activated protein which binds actin. It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins<ref>PMID:15060630</ref>. It is named Adseverin and Scinderin as well. | [[Severin]] is a calcium-activated protein which binds actin. It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins<ref>PMID:15060630</ref>. It is named Adseverin and Scinderin as well. | ||
| - | + | </StructureSection> | |
== 3D Structures of Severin == | == 3D Structures of Severin == | ||
Revision as of 09:54, 28 May 2017
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3D Structures of Severin
3fg6 – Adseverin C-terminal – human
1svy – DdSeverin domain 2 – Dictyostelium discoideum
1svq, 1svr - DdSeverin domain 2 - NMR
References
- ↑ Summerscales J, Dawson JF. Probing Dictyostelium severin structure and function by cross linking to actin. Biochem Cell Biol. 2004 Apr;82(2):343-50. PMID:15060630 doi:http://dx.doi.org/10.1139/o04-002
