Glutathione S-transferase

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Line 21: Line 21:
**[[3uap]] - McGST – ''Methylococcus capsulatus''<br />
**[[3uap]] - McGST – ''Methylococcus capsulatus''<br />
**[[1aw9]] - cGST III – corn<br />
**[[1aw9]] - cGST III – corn<br />
-
**[[1okt]] – PfGST – ''Plasmodium falciparum''<br />
+
**[[1okt]], [[4zxg]] – PfGST – ''Plasmodium falciparum''<br />
**[[3fr6]] - PfGST (mutant) <br />
**[[3fr6]] - PfGST (mutant) <br />
**[[1tw9]] – GST - ''Heligmosomoides polygyrus''<br />
**[[1tw9]] – GST - ''Heligmosomoides polygyrus''<br />
Line 47: Line 47:
**[[4n0v]] – GST N terminal – ''Marinobacter aquaeolei''<br />
**[[4n0v]] – GST N terminal – ''Marinobacter aquaeolei''<br />
**[[4pts]] – GST – ''Gordonia bronchialis''<br />
**[[4pts]] – GST – ''Gordonia bronchialis''<br />
-
 
+
**[[5el8]], [[5ela]], [[5elg]] - AtGST DHAR1 – ''Arabidopsis thaliana''<br />
*''GST binary complex with GSH''
*''GST binary complex with GSH''
Line 86: Line 86:
**[[4nax]] – GST N terminal + GSH – ''Pseudomonas putida''<br />
**[[4nax]] – GST N terminal + GSH – ''Pseudomonas putida''<br />
**[[4pua]] – GST + GSH – ''Streptococcus pneumoniae''<br />
**[[4pua]] – GST + GSH – ''Streptococcus pneumoniae''<br />
 +
**[[5an1]] – GST + GSH – shrimp<br />
*''GST binary complex''
*''GST binary complex''
Line 92: Line 93:
**[[2gsq]] – sqGST + GSH derivative – squid<br />
**[[2gsq]] – sqGST + GSH derivative – squid<br />
**[[2gst]], [[3gst]], [[4gst]], [[5gst]], [[1gss]] - rGST + GSH derivative<br />
**[[2gst]], [[3gst]], [[4gst]], [[5gst]], [[1gss]] - rGST + GSH derivative<br />
-
**[[1gnw]] - AtGST + GSH derivative – ''Arabidopsis thaliana'' <br />
+
**[[1gnw]] - AtGST + GSH derivative <br />
 +
**[[5a4u]] - AtGST + indole aldehyde<br />
 +
**[[5a4v]], [[5a4w]] - AtGST + quercetin<br />
 +
**[[5a5k]] - AtGST + camalexin<br />
**[[1aqv]] - hGST + GSH derivative – human<br />
**[[1aqv]] - hGST + GSH derivative – human<br />
**[[1gtb]], [[1gta]] - SjGST + praziquantel<br />
**[[1gtb]], [[1gta]] - SjGST + praziquantel<br />
Line 109: Line 113:
**[[3qmz]] - yGST + dynein heavy chain<br />
**[[3qmz]] - yGST + dynein heavy chain<br />
**[[2ycd]] - AtGST + GSH derivative<br />
**[[2ycd]] - AtGST + GSH derivative<br />
 +
**[[4yav]] - GST + GSH derivative – ''Sphingobium''<br />
*GST α class
*GST α class
Line 137: Line 142:
**[[3ik9]] - hGST A1-1 + GSDN<br />
**[[3ik9]] - hGST A1-1 + GSDN<br />
**[[4hj2]] - hGST A1-1 + chemotherapeutic drug<br />
**[[4hj2]] - hGST A1-1 + chemotherapeutic drug<br />
 +
**[[5jcu]] - hGST A1-1 + inhibitor<br />
**[[2vct]] - hGST A2-2 + steroid<br />
**[[2vct]] - hGST A2-2 + steroid<br />
**[[2vcv]] - hGST A3-3 + steroid<br />
**[[2vcv]] - hGST A3-3 + steroid<br />
Line 156: Line 162:
**[[4i97]] – GST + GSH – ''Scaptomyza nigrita''<br />
**[[4i97]] – GST + GSH – ''Scaptomyza nigrita''<br />
**[[3wyw]] – GST + GSH – brown planthopper<br />
**[[3wyw]] – GST + GSH – brown planthopper<br />
 +
**[[5f0g]] – DmGST-2 <br />
*GST ε class
*GST ε class
Line 163: Line 170:
**[[2imk]], [[4gsn]] - AgGST + GSH derivative<br />
**[[2imk]], [[4gsn]] - AgGST + GSH derivative<br />
**[[3zmk]], [[3zml]] - GST + GSH – ''Anopheles funestus''<br />
**[[3zmk]], [[3zml]] - GST + GSH – ''Anopheles funestus''<br />
 +
**[[5ft3]] - GST + GSH – ''Aedes aegypti''<br />
 +
**[[4yh2]] - DmGST + GSH <br />
*GST κ class
*GST κ class
Line 182: Line 191:
**[[1xw5]], [[1xw6]] - hGST + GSH<BR />
**[[1xw5]], [[1xw6]] - hGST + GSH<BR />
**[[2f8f]] - mGST (mutant) + GSH<BR />
**[[2f8f]] - mGST (mutant) + GSH<BR />
-
**[[3crt]] - SjGST + GSH<BR />
+
**[[3crt]], [[4wr4]], [[4wr5]] - SjGST + GSH<BR />
**[[3cru]], [[3d0z]] - SjGST (mutant) + GSH<BR />
**[[3cru]], [[3d0z]] - SjGST (mutant) + GSH<BR />
**[[6gst]] - rGST + GSH<br />
**[[6gst]] - rGST + GSH<br />
Line 199: Line 208:
**[[4aki]] – SjGST + ATP<br />
**[[4aki]] – SjGST + ATP<br />
**[[4akh]] – SjGST + AMPPNP <br />
**[[4akh]] – SjGST + AMPPNP <br />
 +
**[[5gzz]] – SjGST + JAR1 + GSH <br />
*GST ν class
*GST ν class
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**[[1bay]] - mGST <br />
**[[1bay]] - mGST <br />
-
**[[10gs]], [[14gs]], [[16gs]], [[1lbk]] - hGST<br />
+
**[[10gs]], [[14gs]], [[16gs]], [[1lbk]], [[5dak]], [[5dal]], [[5dcg]], [[5djm]] - hGST<br />
**[[22gs]], [[1eog]], [[1eoh]], [[3hjm]], [[3hkr]], [[3kmn]] - hGST (mutant)<br />
**[[22gs]], [[1eog]], [[1eoh]], [[3hjm]], [[3hkr]], [[3kmn]] - hGST (mutant)<br />
 +
**[[5djl]] – hGST + GSH <br />
 +
**[[5ddl]] – hGST + GSH + GSH derivative <br />
**[[4ecb]], [[4ecc]] – SjGST/hKininogen peptide<br />
**[[4ecb]], [[4ecc]] – SjGST/hKininogen peptide<br />
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**[[13gs]], [[3csj]] - hGST + drug<br />
**[[13gs]], [[3csj]] - hGST + drug<br />
**[[3ie3]] - hGST (mutant) + drug<br />
**[[3ie3]] - hGST (mutant) + drug<br />
 +
**[[5j41]] – hGST + piperlongumine + GSH <br />
**[[2gsr]] - GST + GSH derivative - pig
**[[2gsr]] - GST + GSH derivative - pig
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**[[1eem]] – hGST<br />
**[[1eem]] – hGST<br />
-
**[[3q18]], [[3vln]], [[4is0]] - hGST (mutant) <br />
+
**[[3vln]], [[4is0]] – hGST-1 (mutant)<br />
-
**[[3rbt]] - siGST <br />
+
**[[3lfl]] – hGST-1 + GSH <br />
-
**[[3lfl]] - hGST + GSH<BR />
+
**[[4yqm]], [[4yqu]], [[4yqv]] – hGST-1 + inhibitor<br />
-
**[[3qag]], [[3q19]] - hGST (mutant) + GSH<BR />
+
**[[3qag]], [[3q19]] – hGST-2 (mutant) + GSH <br />
 +
**[[3q18]] – hGST-2 (mutant)<br />
**[[3wd6]] – GST + GSH – silk moth<br />
**[[3wd6]] – GST + GSH – silk moth<br />
 +
**[[3rbt]] - siGST <br />
*GST ζ class
*GST ζ class
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**[[1gwc]] - GST – wheat<br />
**[[1gwc]] - GST – wheat<br />
 +
**[[5g5e]] - MiGST – ''Mangifera indica''<br />
 +
**[[5g5f]] - MiGST + GSH<br />
 +
**[[5kej]] - MiGST + GSH derivative<br />
**[[2vo4]], [[4chs]] - sGST + GSH derivative – soybean<br />
**[[2vo4]], [[4chs]] - sGST + GSH derivative – soybean<br />
-
**[[4top]] - sGST + GSH<BR />
+
**[[5agy]] - sGST (mutant) + GSH derivative<br />
 +
**[[4top]] - sGST + GSH<BR />
 +
**[[5ecs]] – AtGST + GSH <br />
 +
**[[5ech]], [[5eci]], [[5eck]], [[5ecl]], [[5ecm]], [[5ecn]], [[5eco]] [[5ecp]], [[5ecq]], [[5ecr]] – AtGST + JAR1 + GSH + ATP <br />
*Microsomal GST
*Microsomal GST

Revision as of 08:50, 30 May 2017

Glutathione S-tansferase complex with glutathione (PDB entry 1fhe)

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3D structures of glutathione S-transferase

Updated on 30-May-2017

References

  1. ↑ Oakley A. Glutathione transferases: a structural perspective. Drug Metab Rev. 2011 May;43(2):138-51. doi: 10.3109/03602532.2011.558093. Epub, 2011 Mar 23. PMID:21428697 doi:http://dx.doi.org/10.3109/03602532.2011.558093
  2. ↑ Rossjohn J, Feil SC, Wilce MC, Sexton JL, Spithill TW, Parker MW. Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase. J Mol Biol. 1997 Nov 7;273(4):857-72. PMID:9367777 doi:10.1006/jmbi.1997.1338

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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