Growth differentiation factor
From Proteopedia
(Difference between revisions)
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*'''GDF-2''' or '''bone morphogenetic protein 9''' maintains the response of cholinergic neurons to acetylcholine.<br /> | *'''GDF-2''' or '''bone morphogenetic protein 9''' maintains the response of cholinergic neurons to acetylcholine.<br /> | ||
*'''GDF-5''' is expressed in the central nervous system and is involved in the development of joints and skeleton<ref>PMID:23432680</ref>.<br /> | *'''GDF-5''' is expressed in the central nervous system and is involved in the development of joints and skeleton<ref>PMID:23432680</ref>.<br /> | ||
| - | *'''GDF-8''' or '''myostatin''', controls the growth of muscle tissue<ref>PMID:10610713</ref>. For more details see [[Group:MUZIC:Myostatin]]. | + | *'''GDF-8''' or '''myostatin''', controls the growth of muscle tissue<ref>PMID:10610713</ref>. For more details see [[Group:MUZIC:Myostatin]].<br /> |
| + | *'''GDF-11''' or '''bone morphogenetic protein 11''' is a circulating factor that reverses age-related cardiac hypertrophy<ref>PMID:23663781</ref>. | ||
</StructureSection> | </StructureSection> | ||
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**[[3evs]] – hGDF + bone morphogenetic receptor <br /> | **[[3evs]] – hGDF + bone morphogenetic receptor <br /> | ||
**[[3qb4]] – hGDF (mutant) + bone morphogenetic receptor <br /> | **[[3qb4]] – hGDF (mutant) + bone morphogenetic receptor <br /> | ||
| + | **[[5hk5]] – hGDF + gremlin-2 <br /> | ||
*GDF-8 | *GDF-8 | ||
| + | **[[5ji1]] – mGDF – mouse <br /> | ||
**[[3hh2]] – mGDF + follistatin <br /> | **[[3hh2]] – mGDF + follistatin <br /> | ||
**[[3sek]] – mGDF + follistatin-related protein <br /> | **[[3sek]] – mGDF + follistatin-related protein <br /> | ||
| + | **[[5f3hf]], [[5f3b]] – hGDF + antibody <br /> | ||
| + | |||
| + | *GDF-11 | ||
| + | |||
| + | **[[5uhm]], [[5e4g]] – hGDF <br /> | ||
| + | **[[5jhw]] – hGDF + follistatin <br /> | ||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:38, 4 June 2017
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3D structures of growth differentiation factor
Updated on 04-June-2017
References
- ↑ Jin L, Li X. Growth differentiation factor 5 regulation in bone regeneration. Curr Pharm Des. 2013;19(19):3364-73. PMID:23432680
- ↑ Ferrell RE, Conte V, Lawrence EC, Roth SM, Hagberg JM, Hurley BF. Frequent sequence variation in the human myostatin (GDF8) gene as a marker for analysis of muscle-related phenotypes. Genomics. 1999 Dec 1;62(2):203-7. PMID:10610713 doi:http://dx.doi.org/10.1006/geno.1999.5984
- ↑ Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'Osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ, Lee RT. Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy. Cell. 2013 May 9;153(4):828-39. doi: 10.1016/j.cell.2013.04.015. PMID:23663781 doi:http://dx.doi.org/10.1016/j.cell.2013.04.015
