Lysine-specific histone demethylase
From Proteopedia
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**[[4gu0]] – hLSD2 + histone 3.3 peptide <br /> | **[[4gu0]] – hLSD2 + histone 3.3 peptide <br /> | ||
| - | *lysine-specific demethylase 4A or JMJD2A | + | *lysine-specific demethylase 4A or JMJD2A see [[Jumonji domain-containing protein]] |
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*lysine-specific demethylase 4D or KDM4D | *lysine-specific demethylase 4D or KDM4D | ||
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**[[2yqe]] – hLSD5D ARID domain - NMR<br /> | **[[2yqe]] – hLSD5D ARID domain - NMR<br /> | ||
| - | *lysine-specific demethylase 6B or JMJD3 | + | *lysine-specific demethylase 6B or JMJD3 see [[Jumonji domain-containing protein]] |
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Revision as of 08:15, 26 June 2017
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3D structures of lysine-specific histone demethylase
Updated on 26-June-2017
References
- ↑ Chen Y, Jie W, Yan W, Zhou K, Xiao Y. Lysine-specific histone demethylase 1 (LSD1): A potential molecular target for tumor therapy. Crit Rev Eukaryot Gene Expr. 2012;22(1):53-9. PMID:22339659
- ↑ Pollock JA, Larrea MD, Jasper JS, McDonnell DP, McCafferty DG. Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERalpha-dependent and -independent manners. ACS Chem Biol. 2012 Jul 20;7(7):1221-31. doi: 10.1021/cb300108c. Epub 2012 May, 10. PMID:22533360 doi:http://dx.doi.org/10.1021/cb300108c
- ↑ van Essen D, Zhu Y, Saccani S. A feed-forward circuit controlling inducible NF-kappaB target gene activation by promoter histone demethylation. Mol Cell. 2010 Sep 10;39(5):750-60. doi: 10.1016/j.molcel.2010.08.010. PMID:20832726 doi:http://dx.doi.org/10.1016/j.molcel.2010.08.010
- ↑ Li X, Liu L, Yang S, Song N, Zhou X, Gao J, Yu N, Shan L, Wang Q, Liang J, Xuan C, Wang Y, Shang Y, Shi L. Histone demethylase KDM5B is a key regulator of genome stability. Proc Natl Acad Sci U S A. 2014 May 13;111(19):7096-101. doi:, 10.1073/pnas.1324036111. Epub 2014 Apr 28. PMID:24778210 doi:http://dx.doi.org/10.1073/pnas.1324036111
- ↑ Chen Y, Yang Y, Wang F, Wan K, Yamane K, Zhang Y, Lei M. Crystal structure of human histone lysine-specific demethylase 1 (LSD1). Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):13956-61. Epub 2006 Sep 6. PMID:16956976
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