Methylcitrate synthase

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== Relevance ==
== Relevance ==
The high levels of propionate used to preserve foodstuffs lead to fungal growth inhibition via the accumulation of intermediates of the methylcitrate cycle<ref>PMID:10712680</ref>.
The high levels of propionate used to preserve foodstuffs lead to fungal growth inhibition via the accumulation of intermediates of the methylcitrate cycle<ref>PMID:10712680</ref>.
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See also [[Citrate Synthase]].
See also [[Citrate Synthase]].

Revision as of 06:51, 23 July 2017

Methylcitrate synthase dimer (PDB entry 3tag)

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3D structures of methylcitrate synthase

3hwk – MCS – Mycobacterium tuberculosis
3o8j – MCS – Salmonella enterica
3tqg – MCS – Coxiella burnetii

References

  1. Horswill AR, Escalante-Semerena JC. Salmonella typhimurium LT2 catabolizes propionate via the 2-methylcitric acid cycle. J Bacteriol. 1999 Sep;181(18):5615-23. PMID:10482501
  2. Brock M, Fischer R, Linder D, Buckel W. Methylcitrate synthase from Aspergillus nidulans: implications for propionate as an antifungal agent. Mol Microbiol. 2000 Mar;35(5):961-73. PMID:10712680

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Michal Harel, Alexander Berchansky

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