This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Nucleoporin
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | |||
<StructureSection load='1xip' size='350' side='right' caption='Yeast nucleoporin NUP159 N-terminal domain (PDB entry [[1xip]])' scene='Nucleoporin/Cv/1'> | <StructureSection load='1xip' size='350' side='right' caption='Yeast nucleoporin NUP159 N-terminal domain (PDB entry [[1xip]])' scene='Nucleoporin/Cv/1'> | ||
== Function == | == Function == | ||
| Line 32: | Line 31: | ||
**[[3p3d]] - NUP53 RRM domain - ''Pischia guillermondii''<br /> | **[[3p3d]] - NUP53 RRM domain - ''Pischia guillermondii''<br /> | ||
**[[4lir]] – hNUP53 residues 151-266<br /> | **[[4lir]] – hNUP53 residues 151-266<br /> | ||
| + | **[[5hb8]], [[5hb7]] – CtNUP53 - ''Chaetomium thermophilum''<br /> | ||
| + | **[[5hb3]] – CtNUP53 + NUP NIC96 <br /> | ||
*NUP54 | *NUP54 | ||
**[[3t97]] – rNUP54 + NUP62 - rat<br /> | **[[3t97]] – rNUP54 + NUP62 - rat<br /> | ||
| Line 41: | Line 42: | ||
**[[4jq5]] – hNUP58/45 <br /> | **[[4jq5]] – hNUP58/45 <br /> | ||
*NUP82 | *NUP82 | ||
| - | **[[3pbp]] – yNUP82 NTD + NUP116 CTD + NUP159 | + | **[[3pbp]] – yNUP82 NTD + NUP116 CTD + NUP159 CTD<br /> |
| - | **[[3tkn]] - yNUP82 NTD + NUP98 + NUP159 | + | **[[3tkn]] - yNUP82 NTD + NUP98 + NUP159 CTD<br /> |
| + | **[[5cww]] – CtNUP82 + CtNUP145 CTD peptide + Ct159 CTD peptide<br /> | ||
*NUP84 | *NUP84 | ||
**[[3jro]], [[3iko]] – yNUP84+NUP145+protein Sec13<br /> | **[[3jro]], [[3iko]] – yNUP84+NUP145+protein Sec13<br /> | ||
| Line 68: | Line 70: | ||
**[[3kep]], [[3kes]] – yNUP145 autoproteolytic domain<br /> | **[[3kep]], [[3kes]] – yNUP145 autoproteolytic domain<br /> | ||
**[[3jrp]] - yNUP145+protein Sec13<br /> | **[[3jrp]] - yNUP145+protein Sec13<br /> | ||
| + | **[[5hb5]] – CtNUP145 <br /> | ||
| + | **[[5hb6]] – CtNUP145 (mutant)<br /> | ||
| + | *NUP152 | ||
| + | **[[5tvz]] – yNUP152 Ig-like repeats - NMR<br /> | ||
*NUP153 | *NUP153 | ||
**[[3gj3]], [[3gj4]], [[3gj5]], [[3gj6]], [[3gj7]], [[3gj8]], [[3ch5]] – hNUP153+RAN<br /> | **[[3gj3]], [[3gj4]], [[3gj5]], [[3gj6]], [[3gj7]], [[3gj8]], [[3ch5]] – hNUP153+RAN<br /> | ||
| Line 79: | Line 85: | ||
*NUP170 | *NUP170 | ||
**[[3i5p]], [[3i5q]] – yNUP170<br /> | **[[3i5p]], [[3i5q]] – yNUP170<br /> | ||
| + | **[[5hb1]] – CtNUP170 <br /> | ||
| + | **[[5haz]] – CtNUP170 CTD<br /> | ||
| + | **[[5hay]] – CtNUP170 CTD (mutant)<br /> | ||
| + | **[[5hb0]] – CtNUP170 (mutant) + CtNUP145 peptide<br /> | ||
| + | **[[5hax]] – CtNUP170 NTD + CtNUP53 peptide<br /> | ||
*NUP192 | *NUP192 | ||
**[[4ifq]] – yNUP192<br /> | **[[4ifq]] – yNUP192<br /> | ||
| + | **[[5hb4]] – CtNUP192 <br /> | ||
*NUP214 | *NUP214 | ||
**[[3fmo]], [[3fmp]], [[3fhc]] – hNUP214+dead-box helicase<br /> | **[[3fmo]], [[3fmp]], [[3fhc]] – hNUP214+dead-box helicase<br /> | ||
| Line 101: | Line 113: | ||
**[[2rfo]], [[2qx5]] – yNic96<br /> | **[[2rfo]], [[2qx5]] – yNic96<br /> | ||
| + | **[[5hb2]] – CtNic96 <br /> | ||
**[[1gyb]] – NUP+yNTF2<br /> | **[[1gyb]] – NUP+yNTF2<br /> | ||
}} | }} | ||
Revision as of 06:47, 28 August 2017
| |||||||||||
3D Structures of Nucleoporin
Updated on 28-August-2017
References
- ↑ Doye V, Hurt E. From nucleoporins to nuclear pore complexes. Curr Opin Cell Biol. 1997 Jun;9(3):401-11. PMID:9159086
- ↑ Belanger KD, Kenna MA, Wei S, Davis LI. Genetic and physical interactions between Srp1p and nuclear pore complex proteins Nup1p and Nup2p. J Cell Biol. 1994 Aug;126(3):619-30. PMID:8045927
- ↑ Solsbacher J, Maurer P, Vogel F, Schlenstedt G. Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin alpha. Mol Cell Biol. 2000 Nov;20(22):8468-79. PMID:11046143
- ↑ Cronshaw JM, Matunis MJ. The nuclear pore complex: disease associations and functional correlations. Trends Endocrinol Metab. 2004 Jan-Feb;15(1):34-9. PMID:14693424
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Joel L. Sussman, Alexander Berchansky, Jaime Prilusky
