Phosphoenolpyruvate carboxykinase
From Proteopedia
(Difference between revisions)
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**[[2gmv]] – hPEPCK + inhibitor + PEP + Mn - human<br /> | **[[2gmv]] – hPEPCK + inhibitor + PEP + Mn - human<br /> | ||
**[[2qew]] – rPEPCK + Mn - rat<br /> | **[[2qew]] – rPEPCK + Mn - rat<br /> | ||
| + | **[[5v95]] – rPEPCK (mutant) + Mn <br /> | ||
**[[2qf1]] – rPEPCK + oxaloacetate + Mn<br /> | **[[2qf1]] – rPEPCK + oxaloacetate + Mn<br /> | ||
| - | **[[2rk7]] – rPEPCK + oxalate + Mn<br /> | + | **[[2rk7]], [[4ywb]] – rPEPCK + oxalate + Mn<br /> |
| - | **[[2rk8]], [[2rka]], [[2rkd]], [[2rke]] – rPEPCK + inhibitor + Mn<br /> | + | **[[2rk8]], [[2rka]], [[2rkd]], [[2rke]], [[4yw8]], [[4ywd]] – rPEPCK + inhibitor + Mn<br /> |
**[[4wiu]] – MtPEPCK + oxalate + Mn – ''Mycobacterium tuberculosis''<br /> | **[[4wiu]] – MtPEPCK + oxalate + Mn – ''Mycobacterium tuberculosis''<br /> | ||
**[[4wie]] – MtPEPCK + Mn <br /> | **[[4wie]] – MtPEPCK + Mn <br /> | ||
| + | **[[4wpt]] – MtPEPCK + PEP <br /> | ||
| + | **[[4wpv]] – MtPEPCK (mutant) + Pi + Zn <br /> | ||
*PEPCK GTP driven complex with nucleotide | *PEPCK GTP driven complex with nucleotide | ||
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**[[2fah]] – cPEPCK + GDP + Mn <br /> | **[[2fah]] – cPEPCK + GDP + Mn <br /> | ||
**[[2qey]] – rPEPCK + GTP + Mn<br /> | **[[2qey]] – rPEPCK + GTP + Mn<br /> | ||
| + | **[[5fh0]], [[5fh1]], [[5fh2]], [[5v97]] – rPEPCK (mutant) + Mn + GTP<br /> | ||
**[[4gnm]], [[4gnq]] - rPEPCK + oxalate + GTP + Mn<br /> | **[[4gnm]], [[4gnq]] - rPEPCK + oxalate + GTP + Mn<br /> | ||
**[[4gmw]], [[4gnl]], [[4gnp]] – rPEPCK + PEP + GDP + Mn <br /> | **[[4gmw]], [[4gnl]], [[4gnp]] – rPEPCK + PEP + GDP + Mn <br /> | ||
**[[3dt2]], [[3dt4]], [[4gmu]] – rPEPCK + GTP + oxalate + Mn<br /> | **[[3dt2]], [[3dt4]], [[4gmu]] – rPEPCK + GTP + oxalate + Mn<br /> | ||
| - | **[[3mof]] – rPEPCK (mutant) + GTP + oxalate + Mn<br /> | + | **[[3mof]], [[5fh3]], [[5v9g]] – rPEPCK (mutant) + GTP + oxalate + Mn<br /> |
**[[3dt7]], [[4gmm]], [[4gmz]], [[4gno]] – rPEPCK + GTP + sulfopyruvate + Mn<br /> | **[[3dt7]], [[4gmm]], [[4gmz]], [[4gno]] – rPEPCK + GTP + sulfopyruvate + Mn<br /> | ||
| - | **[[3moe]], [[4ox2]] – rPEPCK (mutant) + GTP + sulfopyruvate + Mn<br /> | + | **[[3moe]], [[4ox2]], [[5fh4]], [[5v9f]] – rPEPCK (mutant) + GTP + sulfopyruvate + Mn<br /> |
**[[3dtb]] – rPEPCK + GTP + phosphoglycolate + Mn<br /> | **[[3dtb]] – rPEPCK + GTP + phosphoglycolate + Mn<br /> | ||
| - | **[[3moh]] – rPEPCK (mutant) + GDP + phosphoglycolate + Mn<br /> | + | **[[3moh]], [[5fh5]], [[5v9h]] – rPEPCK (mutant) + GDP + phosphoglycolate + Mn<br /> |
**[[2qf2]] – rPEPCK + GDP + oxaloacetate + Mn<br /> | **[[2qf2]] – rPEPCK + GDP + oxaloacetate + Mn<br /> | ||
| + | **[[4yw9]] – rPEPCK + inhibitor + Mn + GTP<br /> | ||
**[[4rcg]] – MtPEPCK + GDP + Mg <br /> | **[[4rcg]] – MtPEPCK + GDP + Mg <br /> | ||
**[[4r43]] – MtPEPCK + GDP + Mn <br /> | **[[4r43]] – MtPEPCK + GDP + Mn <br /> | ||
| + | **[[5i67]] – MtPEPCK (mutant) + Mn + GDP<br /> | ||
| + | **[[4wl8]] – MtPEPCK + Mn + GTP analog<br /> | ||
| + | **[[4wou]] – MtPEPCK + Mn + Zn + GDP<br /> | ||
| + | **[[4wpu]] – MtPEPCK (mutant) + PEP + GDP <br /> | ||
*PEPCK | *PEPCK | ||
Revision as of 10:18, 4 September 2017
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3D Structures of PEPCK
Updated on 04-September-2017
References
- ↑ Hanson RW, Reshef L. Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression. Annu Rev Biochem. 1997;66:581-611. PMID:9242918 doi:http://dx.doi.org/10.1146/annurev.biochem.66.1.581
- ↑ Dunten P, Belunis C, Crowther R, Hollfelder K, Kammlott U, Levin W, Michel H, Ramsey GB, Swain A, Weber D, Wertheimer SJ. Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J Mol Biol. 2002 Feb 15;316(2):257-64. PMID:11851336 doi:http://dx.doi.org/10.1006/jmbi.2001.5364
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Michal Harel, Alexander Berchansky, Joel L. Sussman, Jaime Prilusky
