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5arf

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==SMYD2 in complex with small molecule inhibitor==
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==SMYD2 in complex with small molecule inhibitor compound-2==
<StructureSection load='5arf' size='340' side='right' caption='[[5arf]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
<StructureSection load='5arf' size='340' side='right' caption='[[5arf]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5arf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ARF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ARF FirstGlance]. <br>
<table><tr><td colspan='2'>[[5arf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ARF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ARF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I9H:N-[3-(4-CHLOROPHENYL)-1-{N-CYANO-N-[3-(DIFLUOROMETHOXY)PHENYL]CARBAMIMIDOYL}-4,5-DIHYDRO-1H-+PYRAZOL-4-YL]-N-ETHYL-2-HYDROXYACETAMIDE'>I9H</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I9H:N-[3-(4-CHLOROPHENYL)-1-{N-CYANO-N-[3-(DIFLUOROMETHOXY)PHENYL]CARBAMIMIDOYL}-4,5-DIHYDRO-1H-+PYRAZOL-4-YL]-N-ETHYL-2-HYDROXYACETAMIDE'>I9H</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5arf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5arf OCA], [http://pdbe.org/5arf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5arf RCSB], [http://www.ebi.ac.uk/pdbsum/5arf PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5arf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5arf OCA], [http://pdbe.org/5arf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5arf RCSB], [http://www.ebi.ac.uk/pdbsum/5arf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5arf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5arf" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5arf" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Histone methyltransferase|Histone methyltransferase]]
== References ==
== References ==
<references/>
<references/>

Revision as of 10:32, 13 September 2017

SMYD2 in complex with small molecule inhibitor compound-2

5arf, resolution 1.92Å

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