Pre-mRNA-splicing factor
From Proteopedia
(Difference between revisions)
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**[[1x4q]] – hPrp PWI domain - NMR<BR /> | **[[1x4q]] – hPrp PWI domain - NMR<BR /> | ||
| + | **[[4yhu]], [[4yhv]] – yPrp C-terminal - yeast<br /> | ||
| + | **[[4yhw]] – yPrp C-terminal + snRNA<br /> | ||
*Pre-mRNA-splicing factor 3B | *Pre-mRNA-splicing factor 3B | ||
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*Pre-mRNA-splicing factor 8 | *Pre-mRNA-splicing factor 8 | ||
| - | **[[3sbt]], [[4ilh]] – yPrp RNAseH like domain + A1 cistron-splicing factor AAR2 | + | **[[3sbt]], [[4ilh]] – yPrp RNAseH like domain + A1 cistron-splicing factor AAR2 <br /> |
**[[4jk7]], [[4jk9]], [[3e9o]], [[3e9p]], [[3e66]] - yPrp RNA-binding domain <br /> | **[[4jk7]], [[4jk9]], [[3e9o]], [[3e9p]], [[3e66]] - yPrp RNA-binding domain <br /> | ||
**[[4ilj]], [[4jk8]], [[4jka]], [[4jkb]], [[4jkc]], [[4jkd]], [[4jke]], [[4jkf]], [[4jkg]], [[4jkh]] - yPrp RNA-binding domain (mutant)<br /> | **[[4ilj]], [[4jk8]], [[4jka]], [[4jkb]], [[4jkc]], [[4jkd]], [[4jke]], [[4jkf]], [[4jkg]], [[4jkh]] - yPrp RNA-binding domain (mutant)<br /> | ||
**[[3zef]], [[4i43]] – yPrp + A1 cistron-splicing factor AAR2<br /> | **[[3zef]], [[4i43]] – yPrp + A1 cistron-splicing factor AAR2<br /> | ||
**[[2og4]], [[3sbg]] - yPrp Jab1/MPN domain<br /> | **[[2og4]], [[3sbg]] - yPrp Jab1/MPN domain<br /> | ||
| - | **[[4bgd]] – yPrp Jab1/MPN domain + pre-mRNA-splicing helicase BRR2<br /> | + | **[[4bgd]], [[5dca]], [[5m52]], [[5m5p]] – yPrp Jab1/MPN domain + pre-mRNA-splicing helicase BRR2<br /> |
**[[4kit]] – yPrp Jab1/MPN domain + U5 small nuclear ribonucleoprotein helicase <br /> | **[[4kit]] – yPrp Jab1/MPN domain + U5 small nuclear ribonucleoprotein helicase <br /> | ||
**[[4ilg]] – yPrp Jab1/MPN+RNA-binding domains + A1 cistron-splicing factor AAR2 <br /> | **[[4ilg]] – yPrp Jab1/MPN+RNA-binding domains + A1 cistron-splicing factor AAR2 <br /> | ||
| - | **[[4bgd]] – yPrp Jab1/MPN+RNA-binding domains + A1 cistron-splicing factor AAR2 + pre-mRNA-splicing helicase BRR2<br /> | ||
**[[3lru]] – hPrp residues 1831-1990<br /> | **[[3lru]] – hPrp residues 1831-1990<br /> | ||
**[[3e9l]], [[3enb]] – hPrp endonuclease domain<br /> | **[[3e9l]], [[3enb]] – hPrp endonuclease domain<br /> | ||
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**[[2dk4]] – hPrp splicing factor motif domain - NMR<BR /> | **[[2dk4]] – hPrp splicing factor motif domain - NMR<BR /> | ||
| + | **[[1dvk]] – yPrp functional domain <br /> | ||
*Pre-mRNA-splicing factor 19 | *Pre-mRNA-splicing factor 19 | ||
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**[[2ozb]] – hPrp + RNA + tri-snRNP <br /> | **[[2ozb]] – hPrp + RNA + tri-snRNP <br /> | ||
**[[3siu]], [[3siv]] – hPrp + NHP2-like protein + snRNP <br /> | **[[3siu]], [[3siv]] – hPrp + NHP2-like protein + snRNP <br /> | ||
| + | |||
| + | *Pre-mRNA-splicing factor 38A | ||
| + | |||
| + | **[[4rz9]], [[4rza]] – hPrp <br /> | ||
| + | **[[5f5s]] – hPrp + microfibrillar-associated protein 1<br /> | ||
*Pre-mRNA-splicing factor 40 | *Pre-mRNA-splicing factor 40 | ||
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**[[2xau]], [[3kx2]] – yPrp + ADP | **[[2xau]], [[3kx2]] – yPrp + ADP | ||
| + | |||
| + | *Pre-mRNA-splicing factors in spliceosome | ||
| + | |||
| + | **[[3jb9]] – yPrp <br /> | ||
| + | **[[3jcm]], [[5gam]], [[5gan]], [[5gao]], [[5gap]], [[5gmk]], [[5lj3]], [[5lj5]], [[5lqw]], [[5mps]], [[5mq0]], [[5mqf]], [[5wsg]] – yPrp - CryoEM<br /> | ||
| + | **[[3jcr]], [[5o9z]] – hPrp - CryoEM<br /> | ||
*Pre-mRNA-splicing factor cwc2 | *Pre-mRNA-splicing factor cwc2 | ||
Revision as of 09:34, 14 September 2017
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3D Structures of pre-mRNA splicing factors
Updated on 14-September-2017
References
- ↑ Misteli T, Spector DL. RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. Mol Cell. 1999 Jun;3(6):697-705. PMID:10394358
- ↑ McKie AB, McHale JC, Keen TJ, Tarttelin EE, Goliath R, van Lith-Verhoeven JJ, Greenberg J, Ramesar RS, Hoyng CB, Cremers FP, Mackey DA, Bhattacharya SS, Bird AC, Markham AF, Inglehearn CF. Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13). Hum Mol Genet. 2001 Jul 15;10(15):1555-62. PMID:11468273
