Ribosomal protein S19
From Proteopedia
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| - | + | <StructureSection load='2v7f' size='350' side='right' scene='' caption='Ribosomal protein S19 complex with Cl- ion (PDB code [[2v7f]])'> | |
| + | == Function == | ||
| + | [[Ribosomal protein S19]] (RPS19) is one of the 21 proteins which belong to the 30S <scene name='Ribosomal_protein_S19/Cv/2'>small subunit</scene> of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]] or the 30 proteins which belong to the 40S small subunit of the eukaryotic ribosome. It forms a complex with RPS13 that binds to 16S RRNA<ref>PMID:8722009</ref>. | ||
| - | + | == Relevance == | |
| + | RPS19 is a potent anti-inflammatory agent which appears to work primarily by inhibiting MIF signaling<ref>PMID:23252627</ref>. | ||
| + | </StructureSection> | ||
== 3D Structures of Ribosomal protein S19 == | == 3D Structures of Ribosomal protein S19 == | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
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| - | ===S19=== | ||
[[2v7f]] – RPS19 – ''Pyroccocus abyssi''<br /> | [[2v7f]] – RPS19 – ''Pyroccocus abyssi''<br /> | ||
| - | [[1qkh]], [[1qkf]] - TtRPS19 - ''Thermus thermophilus'' – NMR | + | [[1qkh]], [[1qkf]] - TtRPS19 - ''Thermus thermophilus'' – NMR<br /> |
| - | + | [[3a1p]] – TtRPS19 + ribosome maturation factor<br /> | |
| - | + | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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3D Structures of Ribosomal protein S19
Updated on 01-October-2017
2v7f – RPS19 – Pyroccocus abyssi
1qkh, 1qkf - TtRPS19 - Thermus thermophilus – NMR
3a1p – TtRPS19 + ribosome maturation factor
References
- ↑ Wool IG, Chan YL, Gluck A. Structure and evolution of mammalian ribosomal proteins. Biochem Cell Biol. 1995 Nov-Dec;73(11-12):933-47. PMID:8722009
- ↑ Lv J, Huang XR, Klug J, Frohlich S, Lacher P, Xu A, Meinhardt A, Lan HY. Ribosomal protein S19 is a novel therapeutic agent in inflammatory kidney disease. Clin Sci (Lond). 2013 May;124(10):627-37. doi: 10.1042/CS20120526. PMID:23252627 doi:http://dx.doi.org/10.1042/CS20120526
