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1ytf

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|PDB= 1ytf |SIZE=350|CAPTION= <scene name='initialview01'>1ytf</scene>, resolution 2.500&Aring;
|PDB= 1ytf |SIZE=350|CAPTION= <scene name='initialview01'>1ytf</scene>, resolution 2.500&Aring;
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ytf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ytf OCA], [http://www.ebi.ac.uk/pdbsum/1ytf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ytf RCSB]</span>
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[[Category: transcription regulation]]
[[Category: transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:27:16 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:21:32 2008''

Revision as of 22:21, 30 March 2008


PDB ID 1ytf

Drag the structure with the mouse to rotate
, resolution 2.500Å
Ligands: , , ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



YEAST TFIIA/TBP/DNA COMPLEX


Overview

The X-ray crystal structure of the transcription factor IIA (TFIIA) in complex with the TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a four-helix bundle motif that together have a boot-like appearance. The beta-barrel extends the TBP beta-sheet and bridges over the DNA major groove immediately upstream of the TATA box. The four-helix bundle contributes substantially to the surface of the complex available for interaction with additional transcription factors.

About this Structure

1YTF is a Protein complex structure of sequences from Saccharomyces cerevisiae. The following page contains interesting information on the relation of 1YTF with [TATA-Binding Protein]. Full crystallographic information is available from OCA.

Reference

Crystal structure of a yeast TFIIA/TBP/DNA complex., Tan S, Hunziker Y, Sargent DF, Richmond TJ, Nature. 1996 May 9;381(6578):127-51. PMID:8610010

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