Eglin
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1egp.png|left|200px|thumb|Crystal Structure of Leech Eglin. Residues 1-45 (grey) and 46-70 (green) [[1egp]]]] | ||
| - | {{STRUCTURE_1egp| PDB=1egp | SIZE=300| SCENE=Eglin/Cv/1 |right|CAPTION=Cleaved leech Eglin, [[1egp]] }} | ||
| - | + | <StructureSection load='1egp' size='350' side='right' caption='Cleaved leech Eglin. Residues 1-45 (grey) and 46-70 (green) (PDB code [[1egp]]).' scene='Eglin/Cv/1'> | |
| - | + | '''Eglin C''' is a serine proteinase inhibitor isolated from leech. <ref>PMID:3064813</ref> | |
| + | == Relevance == | ||
| + | |||
| + | Eglin C and its mutants are tested as protease inhibitor drugs. | ||
| + | </StructureSection> | ||
== 3D Structures of Eglin == | == 3D Structures of Eglin == | ||
| Line 20: | Line 22: | ||
[[4h4f]] - lEglin-C+ hChymotrypsin – human<br /> | [[4h4f]] - lEglin-C+ hChymotrypsin – human<br /> | ||
| + | == References == | ||
| + | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
| |||||||||||
3D Structures of Eglin
Updated on 19-October-2017
1egp – lEglin-C – leech
1egl - lEglin-C – NMR
1sbn, 1sib, 1cse - lEglin-C+BsSubtilisin – Bacillus subtilis
2sec - lEglin-C+BlSubtilisin – Bacillus licheniformis
1acb - lEglin-C+bChymotrypsinogen – bovine
4b1t, 4b2a, 4b2b, 4b2c - lEglin-C (mutant) +bTrypsin (mutant)
1mee - lEglin-C+BpMesentericopeptidase – Bacillus pumilus
2tec, 3tec, 1tec - lEglin-C+TvThermitase – Thermoactinomyces vulgaris
4h4f - lEglin-C+ hChymotrypsin – human
References
- ↑ McPhalen CA, James MN. Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo. Biochemistry. 1988 Aug 23;27(17):6582-98. PMID:3064813
