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5lmf
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Yeast protein peptide complex== | |
| - | + | <StructureSection load='5lmf' size='340' side='right' caption='[[5lmf]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5lmf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LMF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LMF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lmf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lmf OCA], [http://pdbe.org/5lmf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lmf RCSB], [http://www.ebi.ac.uk/pdbsum/5lmf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lmf ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PAT1_YEAST PAT1_YEAST]] Activator of decapping that functions as a general and active mechanism of translational repression and required for P-body formation. First decay factor recruited to mRNA, at a time when the mRNA is still associated with translation factors. Subsequently, PAT1 recruits the hepta-heterodimer LSM1-LSM7 complex to P-bodies. In association with the LSM1-LSM7 complex, stabilizes the 3' terminus of mRNAs. This association is also required for mosaic virus genomic RNA translation. Modulates the rates of mRNA-decapping that occur following deadenylation. Might be required for promoting the formation or the stabilization of the preinitiation translation complexes. Required for 40S ribosomal subunit joining to capped and/or polyadenylated mRNA. With other P-body components, enhances the formation of retrotransposition-competent Ty1 virus-like particles. Necessary for accurate chromosome transmission during cell division.<ref>PMID:8816497</ref> <ref>PMID:8972867</ref> <ref>PMID:10523645</ref> <ref>PMID:10394921</ref> <ref>PMID:10747033</ref> <ref>PMID:10779343</ref> <ref>PMID:10913177</ref> <ref>PMID:11027264</ref> <ref>PMID:10761922</ref> <ref>PMID:11514438</ref> <ref>PMID:12773554</ref> <ref>PMID:16179257</ref> <ref>PMID:17875743</ref> <ref>PMID:17429074</ref> <ref>PMID:17513695</ref> <ref>PMID:18086885</ref> <ref>PMID:19901074</ref> <ref>PMID:20832728</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Back, R]] | [[Category: Back, R]] | ||
| + | [[Category: Charenton, C]] | ||
| + | [[Category: Fourati, Z]] | ||
| + | [[Category: Gaudon-Plesse, C]] | ||
[[Category: Graille, M]] | [[Category: Graille, M]] | ||
| + | [[Category: Kolesnikova, O]] | ||
[[Category: Seraphin, B]] | [[Category: Seraphin, B]] | ||
| - | [[Category: Charenton, C]] | ||
| - | [[Category: Gaudon-Plesse, C]] | ||
| - | [[Category: Fourati, Z]] | ||
[[Category: Taverniti, V]] | [[Category: Taverniti, V]] | ||
| - | [[Category: | + | [[Category: Isomerase]] |
| + | [[Category: Protein peptide complex]] | ||
| + | [[Category: Rna binding protein]] | ||
Revision as of 09:19, 1 November 2017
Yeast protein peptide complex
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