4y93

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<StructureSection load='4y93' size='340' side='right' caption='[[4y93]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
<StructureSection load='4y93' size='340' side='right' caption='[[4y93]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4y93]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y93 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4y93]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y93 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=746:4-TERT-BUTYL-N-[2-METHYL-3-(4-METHYL-6-{[4-(MORPHOLIN-4-YLCARBONYL)PHENYL]AMINO}-5-OXO-4,5-DIHYDROPYRAZIN-2-YL)PHENYL]BENZAMIDE'>746</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=746:4-TERT-BUTYL-N-[2-METHYL-3-(4-METHYL-6-{[4-(MORPHOLIN-4-YLCARBONYL)PHENYL]AMINO}-5-OXO-4,5-DIHYDROPYRAZIN-2-YL)PHENYL]BENZAMIDE'>746</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y94|4y94]], [[4y95|4y95]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y94|4y94]], [[4y95|4y95]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BTK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y93 OCA], [http://pdbe.org/4y93 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y93 RCSB], [http://www.ebi.ac.uk/pdbsum/4y93 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y93 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y93 OCA], [http://pdbe.org/4y93 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y93 RCSB], [http://www.ebi.ac.uk/pdbsum/4y93 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y93 ProSAT]</span></td></tr>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bovin]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Kuriyan, J]]
[[Category: Kuriyan, J]]
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[[Category: Btk]]
[[Category: Btk]]
[[Category: Ph-th]]
[[Category: Ph-th]]
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[[Category: Transferase]]
[[Category: Tyrosine kinase]]
[[Category: Tyrosine kinase]]

Revision as of 12:18, 6 November 2017

Crystal structure of the PH-TH-kinase construct of Bruton's tyrosine kinase (Btk)

4y93, resolution 1.69Å

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