4y95
From Proteopedia
(Difference between revisions)
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<StructureSection load='4y95' size='340' side='right' caption='[[4y95]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='4y95' size='340' side='right' caption='[[4y95]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4y95]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y95 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y95 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4y95]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y95 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y95 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=746:4-TERT-BUTYL-N-[2-METHYL-3-(4-METHYL-6-{[4-(MORPHOLIN-4-YLCARBONYL)PHENYL]AMINO}-5-OXO-4,5-DIHYDROPYRAZIN-2-YL)PHENYL]BENZAMIDE'>746</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=746:4-TERT-BUTYL-N-[2-METHYL-3-(4-METHYL-6-{[4-(MORPHOLIN-4-YLCARBONYL)PHENYL]AMINO}-5-OXO-4,5-DIHYDROPYRAZIN-2-YL)PHENYL]BENZAMIDE'>746</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y93|4y93]], [[4y94|4y94]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y93|4y93]], [[4y94|4y94]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BTK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y95 OCA], [http://pdbe.org/4y95 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y95 RCSB], [http://www.ebi.ac.uk/pdbsum/4y95 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y95 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y95 OCA], [http://pdbe.org/4y95 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y95 RCSB], [http://www.ebi.ac.uk/pdbsum/4y95 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y95 ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Bovin]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
[[Category: Kuriyan, J]] | [[Category: Kuriyan, J]] | ||
Revision as of 12:18, 6 November 2017
Crystal structure of the kinase domain of Bruton's tyrosine kinase with mutations in the activation loop
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