This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4eqz
From Proteopedia
| Line 12: | Line 12: | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/DOT1L_HUMAN DOT1L_HUMAN]] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. | [[http://www.uniprot.org/uniprot/DOT1L_HUMAN DOT1L_HUMAN]] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. | ||
| - | |||
| - | ==See Also== | ||
| - | *[[Histone methyltransferase|Histone methyltransferase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| Line 38: | Line 35: | ||
[[Category: Histone]] | [[Category: Histone]] | ||
[[Category: Methyltransferase]] | [[Category: Methyltransferase]] | ||
| + | [[Category: Sgc]] | ||
[[Category: Transferase-transferase inhibitor complex]] | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 08:07, 15 November 2017
Crystal structure of human DOT1L in complex with inhibitor FED2
| |||||||||||
Categories: Histone-lysine N-methyltransferase | Human | Arrowsmith, C H | Bountra, C | Bradner, J E | Brown, P J | Edwards, A M | Federation, A | Li, Y | Marineau, J | Nguyen, K T | Qi, J | Structural genomic | Schapira, M | Tempel, W | Vedadi, M | Wernimont, A K | Yu, W | Epigenetic | Histone | Methyltransferase | Sgc | Transferase-transferase inhibitor complex
