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5uet

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'''Unreleased structure'''
 
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The entry 5uet is ON HOLD until Jan 03 2019
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==BRD4_BD2_A-1308586==
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<StructureSection load='5uet' size='340' side='right' caption='[[5uet]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
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Authors: Park, C.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5uet]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UET OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UET FirstGlance]. <br>
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Description: BRD4_BD2_A-1308586
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=87V:2-methyl-5-phenyl-1H-pyrrole-3-carboxamide'>87V</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5uf0|5uf0]], [[5uez|5uez]], [[5uey|5uey]], [[5uex|5uex]], [[5uev|5uev]], [[5uep|5uep]], [[5ues|5ues]], [[5uer|5uer]], [[5ueq|5ueq]], [[5uew|5uew]], [[5ueo|5ueo]], [[5ueu|5ueu]]</td></tr>
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[[Category: Park, C.H]]
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uet FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uet OCA], [http://pdbe.org/5uet PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uet RCSB], [http://www.ebi.ac.uk/pdbsum/5uet PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uet ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
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== Function ==
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[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Human]]
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[[Category: Park, C H]]
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[[Category: Signaling protein-inhibitor complex]]

Revision as of 10:00, 16 November 2017

BRD4_BD2_A-1308586

5uet, resolution 2.29Å

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