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5gi4

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'''Unreleased structure'''
 
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The entry 5gi4 is ON HOLD until Paper Publication
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==DEAD-box RNA helicase==
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<StructureSection load='5gi4' size='340' side='right' caption='[[5gi4]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5gi4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GI4 FirstGlance]. <br>
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Description:
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">deaD, csdA, mssB, rhlD, b3162, JW5531 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gi4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gi4 OCA], [http://pdbe.org/5gi4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gi4 RCSB], [http://www.ebi.ac.uk/pdbsum/5gi4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gi4 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/DEAD_ECOLI DEAD_ECOLI]] DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity at low temperature. Involved in 50S ribosomal subunit assembly, acting after SrmB, and could also play a role in the biogenesis of the 30S ribosomal subunit. In addition, is involved in mRNA decay, via formation of a cold-shock degradosome with RNase E. Also stimulates translation of some mRNAs, probably at the level of initiation.[HAMAP-Rule:MF_00964]<ref>PMID:10216955</ref> <ref>PMID:15148362</ref> <ref>PMID:15196029</ref> <ref>PMID:15554978</ref> <ref>PMID:17259309</ref> <ref>PMID:8552679</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Ecoli]]
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[[Category: RNA helicase]]
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[[Category: Li, F]]
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[[Category: Shi, Y]]
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[[Category: Wang, L]]
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[[Category: Wu, L]]
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[[Category: Xu, L]]
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[[Category: Dimer]]
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[[Category: Hydrolase]]
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[[Category: Reca-like]]
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[[Category: Rna helicase]]
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[[Category: Wild type]]

Revision as of 11:32, 16 November 2017

DEAD-box RNA helicase

5gi4, resolution 2.24Å

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