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2bvs

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|PDB= 2bvs |SIZE=350|CAPTION= <scene name='initialview01'>2bvs</scene>, resolution 1.40&Aring;
|PDB= 2bvs |SIZE=350|CAPTION= <scene name='initialview01'>2bvs</scene>, resolution 1.40&Aring;
|SITE= <scene name='pdbsite=AC1:2ce+Binding+Site+For+Chain+H'>AC1</scene>
|SITE= <scene name='pdbsite=AC1:2ce+Binding+Site+For+Chain+H'>AC1</scene>
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|LIGAND= <scene name='pdbligand=2CE:N-[2-(2-CARBAMOYLMETHOXY-ETHOXY)-ETHYL]-2-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDE'>2CE</scene>
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|LIGAND= <scene name='pdbligand=2CE:N-[2-(2-CARBAMOYLMETHOXY-ETHOXY)-ETHYL]-2-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDE'>2CE</scene>, <scene name='pdbligand=TYS:SULFONATED+TYROSINE'>TYS</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span>
|GENE=
|GENE=
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|DOMAIN=
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|RELATEDENTRY=[[1a2c|1A2C]], [[1a3b|1A3B]], [[1a3e|1A3E]], [[1a46|1A46]], [[1a4w|1A4W]], [[1a5g|1A5G]], [[1a61|1A61]], [[1abi|1ABI]], [[1abj|1ABJ]], [[1ad8|1AD8]], [[1ae8|1AE8]], [[1afe|1AFE]], [[1aht|1AHT]], [[1ai8|1AI8]], [[1aix|1AIX]], [[1awf|1AWF]], [[1awh|1AWH]], [[1ay6|1AY6]], [[1b5g|1B5G]], [[1b7x|1B7X]], [[1ba8|1BA8]], [[1bb0|1BB0]], [[1bcu|1BCU]], [[1bhx|1BHX]], [[1bmm|1BMM]], [[1bmn|1BMN]], [[1bth|1BTH]], [[1c1u|1C1U]], [[1c1v|1C1V]], [[1c1w|1C1W]], [[1c4u|1C4U]], [[1c4v|1C4V]], [[1c4y|1C4Y]], [[1c5l|1C5L]], [[1c5n|1C5N]], [[1c5o|1C5O]], [[1ca8|1CA8]], [[1d3d|1D3D]], [[1d3p|1D3P]], [[1d3q|1D3Q]], [[1d3t|1D3T]], [[1d4p|1D4P]], [[1d6w|1D6W]], [[1d9i|1D9I]], [[1de7|1DE7]], [[1dit|1DIT]], [[1dm4|1DM4]], [[1doj|1DOJ]], [[1dwb|1DWB]], [[1dwc|1DWC]], [[1dwd|1DWD]], [[1dwe|1DWE]], [[1dx5|1DX5]], [[1e0f|1E0F]], [[1eb1|1EB1]], [[1eoj|1EOJ]], [[1eol|1EOL]], [[1fpc|1FPC]], [[1fph|1FPH]], [[1g30|1G30]], [[1g32|1G32]], [[1g37|1G37]], [[1ghv|1GHV]], [[1ghw|1GHW]], [[1ghx|1GHX]], [[1ghy|1GHY]], [[1gj4|1GJ4]], [[1gj5|1GJ5]], [[1h8d|1H8D]], [[1h8i|1H8I]], [[1hag|1HAG]], [[1hah|1HAH]], [[1hai|1HAI]], [[1hao|1HAO]], [[1hap|1HAP]], [[1hbt|1HBT]], [[1hdt|1HDT]], [[1hgt|1HGT]], [[1hlt|1HLT]], [[1hut|1HUT]], [[1hxe|1HXE]], [[1hxf|1HXF]], [[1ihs|1IHS]], [[1iht|1IHT]], [[1jmo|1JMO]], [[1jou|1JOU]], [[1jwt|1JWT]], [[1k21|1K21]], [[1k22|1K22]], [[1kts|1KTS]], [[1ktt|1KTT]], [[1lhc|1LHC]], [[1lhd|1LHD]], [[1lhe|1LHE]], [[1lhf|1LHF]], [[1lhg|1LHG]], [[1mh0|1MH0]], [[1mu6|1MU6]], [[1mu8|1MU8]], [[1mue|1MUE]], [[1nm6|1NM6]], [[1no9|1NO9]], [[1nrn|1NRN]], [[1nro|1NRO]], [[1nrp|1NRP]], [[1nrq|1NRQ]], [[1nrr|1NRR]], [[1nrs|1NRS]], [[1nt1|1NT1]], [[1nu7|1NU7]], [[1nu9|1NU9]], [[1ny2|1NY2]], [[1nzq|1NZQ]], [[1o0d|1O0D]], [[1o2g|1O2G]], [[1o5g|1O5G]], [[1ook|1OOK]], [[1oyt|1OYT]], [[1p8v|1P8V]], [[1ppb|1PPB]], [[1qbv|1QBV]], [[1qhr|1QHR]], [[1qj1|1QJ1]], [[1qj6|1QJ6]], [[1qj7|1QJ7]], [[1qur|1QUR]], [[1qvh|1QVH]], [[1rd3|1RD3]], [[1riw|1RIW]], [[1sb1|1SB1]], [[1sfq|1SFQ]], [[1sg8|1SG8]], [[1sgi|1SGI]], [[1shh|1SHH]], [[1sl3|1SL3]], [[1sr5|1SR5]], [[1t4u|1T4U]], [[1t4v|1T4V]], [[1ta2|1TA2]], [[1ta6|1TA6]], [[1tb6|1TB6]], [[1tbz|1TBZ]], [[1thp|1THP]], [[1thr|1THR]], [[1ths|1THS]], [[1tmb|1TMB]], [[1tmt|1TMT]], [[1tmu|1TMU]], [[1tom|1TOM]], [[1tq0|1TQ0]], [[1tq7|1TQ7]], [[1twx|1TWX]], [[1uma|1UMA]], [[1uvs|1UVS]], [[1vr1|1VR1]], [[1vzq|1VZQ]], [[1w7g|1W7G]], [[1way|1WAY]], [[1wbg|1WBG]], [[1xm1|1XM1]], [[1xmn|1XMN]], [[1zrb|1ZRB]], [[2hgt|2HGT]], [[2hnt|2HNT]], [[2hpp|2HPP]], [[2hpq|2HPQ]], [[2thf|2THF]], [[3hat|3HAT]], [[3htc|3HTC]], [[4htc|4HTC]], [[4thn|4THN]], [[5gds|5GDS]], [[7kme|7KME]], [[8kme|8KME]], [[2bvr|2BVR]], [[2bvx|2BVX]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bvs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bvs OCA], [http://www.ebi.ac.uk/pdbsum/2bvs PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2bvs RCSB]</span>
}}
}}
'''HUMAN THROMBIN COMPLEXED WITH FRAGMENT-BASED SMALL MOLECULES OCCUPYING THE S1 POCKET'''
'''HUMAN THROMBIN COMPLEXED WITH FRAGMENT-BASED SMALL MOLECULES OCCUPYING THE S1 POCKET'''
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==Disease==
 
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Known diseases associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
 
==About this Structure==
==About this Structure==
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[[Category: Sekul, R.]]
[[Category: Sekul, R.]]
[[Category: Tomandl, D.]]
[[Category: Tomandl, D.]]
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[[Category: 2CE]]
 
[[Category: coagulation]]
[[Category: coagulation]]
[[Category: hydrolase]]
[[Category: hydrolase]]
[[Category: serine protease]]
[[Category: serine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:07:24 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:12:29 2008''

Revision as of 23:12, 30 March 2008

Image:2bvs.jpg


PDB ID 2bvs

Drag the structure with the mouse to rotate
, resolution 1.40Å
Sites:
Ligands: ,
Activity: Thrombin, with EC number 3.4.21.5
Related: 1A2C, 1A3B, 1A3E, 1A46, 1A4W, 1A5G, 1A61, 1ABI, 1ABJ, 1AD8, 1AE8, 1AFE, 1AHT, 1AI8, 1AIX, 1AWF, 1AWH, 1AY6, 1B5G, 1B7X, 1BA8, 1BB0, 1BCU, 1BHX, 1BMM, 1BMN, 1BTH, 1C1U, 1C1V, 1C1W, 1C4U, 1C4V, 1C4Y, 1C5L, 1C5N, 1C5O, 1CA8, 1D3D, 1D3P, 1D3Q, 1D3T, 1D4P, 1D6W, 1D9I, 1DE7, 1DIT, 1DM4, 1DOJ, 1DWB, 1DWC, 1DWD, 1DWE, 1DX5, 1E0F, 1EB1, 1EOJ, 1EOL, 1FPC, 1FPH, 1G30, 1G32, 1G37, 1GHV, 1GHW, 1GHX, 1GHY, 1GJ4, 1GJ5, 1H8D, 1H8I, 1HAG, 1HAH, 1HAI, 1HAO, 1HAP, 1HBT, 1HDT, 1HGT, 1HLT, 1HUT, 1HXE, 1HXF, 1IHS, 1IHT, 1JMO, 1JOU, 1JWT, 1K21, 1K22, 1KTS, 1KTT, 1LHC, 1LHD, 1LHE, 1LHF, 1LHG, 1MH0, 1MU6, 1MU8, 1MUE, 1NM6, 1NO9, 1NRN, 1NRO, 1NRP, 1NRQ, 1NRR, 1NRS, 1NT1, 1NU7, 1NU9, 1NY2, 1NZQ, 1O0D, 1O2G, 1O5G, 1OOK, 1OYT, 1P8V, 1PPB, 1QBV, 1QHR, 1QJ1, 1QJ6, 1QJ7, 1QUR, 1QVH, 1RD3, 1RIW, 1SB1, 1SFQ, 1SG8, 1SGI, 1SHH, 1SL3, 1SR5, 1T4U, 1T4V, 1TA2, 1TA6, 1TB6, 1TBZ, 1THP, 1THR, 1THS, 1TMB, 1TMT, 1TMU, 1TOM, 1TQ0, 1TQ7, 1TWX, 1UMA, 1UVS, 1VR1, 1VZQ, 1W7G, 1WAY, 1WBG, 1XM1, 1XMN, 1ZRB, 2HGT, 2HNT, 2HPP, 2HPQ, 2THF, 3HAT, 3HTC, 4HTC, 4THN, 5GDS, 7KME, 8KME, 2BVR, 2BVX


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



HUMAN THROMBIN COMPLEXED WITH FRAGMENT-BASED SMALL MOLECULES OCCUPYING THE S1 POCKET


About this Structure

2BVS is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 02:12:29 2008

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