1bqo
From Proteopedia
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==DISCOVERY OF POTENT, ACHIRAL MATRIX METALLOPROTEINASE INHIBITORS== | ==DISCOVERY OF POTENT, ACHIRAL MATRIX METALLOPROTEINASE INHIBITORS== | ||
<StructureSection load='1bqo' size='340' side='right' caption='[[1bqo]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='1bqo' size='340' side='right' caption='[[1bqo]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=N25:1,3-BIS-(4-METHOXY-BENZENESULFONYL)-5,5-DIMETHYL-HEXAHYDRO-PYRIMIDINE-2-CARBOXYLIC+ACID+HYDROXYAMIDE'>N25</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=N25:1,3-BIS-(4-METHOXY-BENZENESULFONYL)-5,5-DIMETHYL-HEXAHYDRO-PYRIMIDINE-2-CARBOXYLIC+ACID+HYDROXYAMIDE'>N25</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Stromelysin_1 Stromelysin 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.17 3.4.24.17] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Stromelysin_1 Stromelysin 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.17 3.4.24.17] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bqo OCA], [http://pdbe.org/1bqo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bqo RCSB], [http://www.ebi.ac.uk/pdbsum/1bqo PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bqo OCA], [http://pdbe.org/1bqo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bqo RCSB], [http://www.ebi.ac.uk/pdbsum/1bqo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bqo ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bqo ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bqo ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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| - | ==See Also== | ||
| - | *[[Matrix metalloproteinase|Matrix metalloproteinase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 08:19, 29 November 2017
DISCOVERY OF POTENT, ACHIRAL MATRIX METALLOPROTEINASE INHIBITORS
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Categories: Human | Stromelysin 1 | Almstead, N G | Anastasio, M V | De, B | Dunaway, C M | Dunham, K L.M | Gu, F | Mcphail, S J | Mieling, G E | Natchus, M G | Pikul, S | Rydel, T J | Snider, C E | Taiwo, Y O | Matrix metalloprotease | Metalloprotease | Osteoarthritis | Stromelysin | Structure-based drug design
