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1bqo

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==DISCOVERY OF POTENT, ACHIRAL MATRIX METALLOPROTEINASE INHIBITORS==
==DISCOVERY OF POTENT, ACHIRAL MATRIX METALLOPROTEINASE INHIBITORS==
<StructureSection load='1bqo' size='340' side='right' caption='[[1bqo]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1bqo' size='340' side='right' caption='[[1bqo]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=N25:1,3-BIS-(4-METHOXY-BENZENESULFONYL)-5,5-DIMETHYL-HEXAHYDRO-PYRIMIDINE-2-CARBOXYLIC+ACID+HYDROXYAMIDE'>N25</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=N25:1,3-BIS-(4-METHOXY-BENZENESULFONYL)-5,5-DIMETHYL-HEXAHYDRO-PYRIMIDINE-2-CARBOXYLIC+ACID+HYDROXYAMIDE'>N25</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Stromelysin_1 Stromelysin 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.17 3.4.24.17] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Stromelysin_1 Stromelysin 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.17 3.4.24.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bqo OCA], [http://pdbe.org/1bqo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bqo RCSB], [http://www.ebi.ac.uk/pdbsum/1bqo PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bqo OCA], [http://pdbe.org/1bqo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bqo RCSB], [http://www.ebi.ac.uk/pdbsum/1bqo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bqo ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bqo ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bqo ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
 
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*[[Matrix metalloproteinase|Matrix metalloproteinase]]
 
== References ==
== References ==
<references/>
<references/>

Revision as of 08:19, 29 November 2017

DISCOVERY OF POTENT, ACHIRAL MATRIX METALLOPROTEINASE INHIBITORS

1bqo, resolution 2.30Å

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