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5uph
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Lipids bound lysosomal integral membrane protein 2== | |
| - | + | <StructureSection load='5uph' size='340' side='right' caption='[[5uph]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5uph]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UPH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UPH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=M6D:6-O-PHOSPHONO-BETA-D-MANNOPYRANOSE'>M6D</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uph OCA], [http://pdbe.org/5uph PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uph RCSB], [http://www.ebi.ac.uk/pdbsum/5uph PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uph ProSAT]</span></td></tr> |
| - | [[Category: Conrad, K | + | </table> |
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/SCRB2_HUMAN SCRB2_HUMAN]] Unverricht-Lundborg disease;Gaucher disease type 1;Action myoclonus - renal failure syndrome. The disease is caused by mutations affecting the gene represented in this entry. Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher disease. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SCRB2_HUMAN SCRB2_HUMAN]] Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.<ref>PMID:18022370</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Conrad, K S]] | ||
[[Category: Liu, S]] | [[Category: Liu, S]] | ||
| + | [[Category: Lysosomal integral membrane protein 2]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Phospholipid receptor]] | ||
Revision as of 06:57, 13 December 2017
Lipids bound lysosomal integral membrane protein 2
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