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5oec

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'''Unreleased structure'''
 
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The entry 5oec is ON HOLD until Paper Publication
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==Human Rab32 (18-201):GDP in complex with Salmonella GtgE (21-214) C45A mutant==
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<StructureSection load='5oec' size='340' side='right' caption='[[5oec]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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Authors: Wachtel, R., Braeuning, B., Mader, S.L., Ecker, F., Kaila, V.R.I., Groll, M., Itzen, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5oec]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OEC FirstGlance]. <br>
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Description: Human Rab32 (18-201):GDP in complex with Salmonella GtgE (21-214) C45A mutant
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cym|4cym]], [[4mi7|4mi7]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oec OCA], [http://pdbe.org/5oec PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oec RCSB], [http://www.ebi.ac.uk/pdbsum/5oec PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oec ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RAB32_HUMAN RAB32_HUMAN]] Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.<ref>PMID:12186851</ref> <ref>PMID:21255211</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Braeuning, B]]
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[[Category: Ecker, F]]
[[Category: Groll, M]]
[[Category: Groll, M]]
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[[Category: Braeuning, B]]
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[[Category: Itzen, A]]
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[[Category: Kaila, V R.I]]
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[[Category: Mader, S L]]
[[Category: Wachtel, R]]
[[Category: Wachtel, R]]
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[[Category: Kaila, V.R.I]]
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[[Category: Hydrolase]]
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[[Category: Itzen, A]]
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[[Category: Posttranslational modification]]
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[[Category: Mader, S.L]]
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[[Category: Proteolysis]]
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[[Category: Ecker, F]]
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[[Category: Rab gtpase]]
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[[Category: Salmonella infection]]

Revision as of 08:22, 10 January 2018

Human Rab32 (18-201):GDP in complex with Salmonella GtgE (21-214) C45A mutant

5oec, resolution 2.30Å

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