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2dc3
From Proteopedia
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|PDB= 2dc3 |SIZE=350|CAPTION= <scene name='initialview01'>2dc3</scene>, resolution 1.68Å | |PDB= 2dc3 |SIZE=350|CAPTION= <scene name='initialview01'>2dc3</scene>, resolution 1.68Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= CYGB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= CYGB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dc3 OCA], [http://www.ebi.ac.uk/pdbsum/2dc3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2dc3 RCSB]</span> | ||
}} | }} | ||
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[[Category: Sugimoto, H.]] | [[Category: Sugimoto, H.]] | ||
[[Category: Yoshizato, K.]] | [[Category: Yoshizato, K.]] | ||
| - | [[Category: ACY]] | ||
| - | [[Category: HEM]] | ||
[[Category: cytoglobin]] | [[Category: cytoglobin]] | ||
[[Category: heme]] | [[Category: heme]] | ||
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[[Category: structural genomic]] | [[Category: structural genomic]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:32:41 2008'' |
Revision as of 23:32, 30 March 2008
| |||||||
| , resolution 1.68Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Gene: | CYGB (Homo sapiens) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of human cytoglobin at 1.68 angstroms resolution
Overview
Cytoglobin (Cgb) is a recently discovered member of the vertebrate haem-containing globin family. The structure of a new crystal form of wild-type human Cgb (space group C2) was determined at a resolution of 1.68 Angstrom. The results show the presence of an additional helix in the N-terminal residues (4-20) prior to the A helix and an ordered loop structure in the C-terminal region (168-188), while these extended peptides were invisible owing to disorder in the previously reported structures using a P3(2)21 crystal at a resolution of 2.4 Angstrom. A detailed comparison of the two crystal structures shows differences in the conformation of the residues (i.e. Arg84) in the haem environment owing to a different dimeric arrangement.
About this Structure
2DC3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
High-resolution structure of human cytoglobin: identification of extra N- and C-termini and a new dimerization mode., Makino M, Sugimoto H, Sawai H, Kawada N, Yoshizato K, Shiro Y, Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):671-7. Epub 2006, May 12. PMID:16699195
Page seeded by OCA on Mon Mar 31 02:32:41 2008
Categories: Homo sapiens | Single protein | Kawada, N. | Makino, M. | RSGI, RIKEN Structural Genomics/Proteomics Initiative. | Sawai, H. | Shiro, Y. | Sugimoto, H. | Yoshizato, K. | Cytoglobin | Heme | Myoglobin | Oxygen storage | Oxygen transport | Riken structural genomics/proteomics initiative | Rsgi | Structural genomic
