This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6bcz
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='6bcz' size='340' side='right' caption='[[6bcz]], [[Resolution|resolution]] 2.23Å' scene=''> | <StructureSection load='6bcz' size='340' side='right' caption='[[6bcz]], [[Resolution|resolution]] 2.23Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6bcz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BCZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BCZ FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6bcz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BCZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BCZ FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D7Y:tert-butyl+(2-{[(2R)-3-oxo-2-[(propan-2-yl)amino]-3-{[(pyridin-3-yl)methyl]amino}propyl]sulfanyl}ethyl)carbamate'>D7Y</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D7Y:tert-butyl+(2-{[(2R)-3-oxo-2-[(propan-2-yl)amino]-3-{[(pyridin-3-yl)methyl]amino}propyl]sulfanyl}ethyl)carbamate'>D7Y</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6bd6|6bd6]], [[6bd5|6bd5]], [[6bd7|6bd7]], [[6bd8|6bd8]], [[6bdh|6bdh]], [[6bdi|6bdi]], [[6bdk|6bdk]], [[6bdm|6bdm]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6bd6|6bd6]], [[6bd5|6bd5]], [[6bd7|6bd7]], [[6bd8|6bd8]], [[6bdh|6bdh]], [[6bdi|6bdi]], [[6bdk|6bdk]], [[6bdm|6bdm]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYP3A4, CYP3A3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bcz OCA], [http://pdbe.org/6bcz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bcz RCSB], [http://www.ebi.ac.uk/pdbsum/6bcz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bcz ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bcz OCA], [http://pdbe.org/6bcz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bcz RCSB], [http://www.ebi.ac.uk/pdbsum/6bcz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bcz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| Line 14: | Line 15: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Sevrioukova, I]] | [[Category: Sevrioukova, I]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Monooxygenase]] | [[Category: Monooxygenase]] | ||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
Revision as of 08:24, 17 January 2018
Crystal structure of human CYP3A4 bound to an inhibitor
| |||||||||||
