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3kw6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of a domain of 26S proteasome regulatory subunit 8 from homo sapiens. Northeast Structural Genomics Consortium target id HR3102A== | |
| - | + | <StructureSection load='3kw6' size='340' side='right' caption='[[3kw6]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3kw6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KW6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KW6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PSMC5, SUG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kw6 OCA], [http://pdbe.org/3kw6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kw6 RCSB], [http://www.ebi.ac.uk/pdbsum/3kw6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kw6 ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PRS8_HUMAN PRS8_HUMAN]] The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kw/3kw6_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kw6 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Acton, T B]] | ||
| + | [[Category: Baran, M C]] | ||
| + | [[Category: Cunningham, K]] | ||
| + | [[Category: Hunt, J F]] | ||
| + | [[Category: Janjua, H]] | ||
| + | [[Category: Liu, J]] | ||
| + | [[Category: Montelione, G T]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Owens, L]] | ||
| + | [[Category: Seetharaman, J]] | ||
| + | [[Category: Su, M]] | ||
| + | [[Category: Tong, L]] | ||
| + | [[Category: Wang, D]] | ||
| + | [[Category: Xiao, R]] | ||
| + | [[Category: Acetylation]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Cytoplasm]] | ||
| + | [[Category: Nesg]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Nucleus]] | ||
| + | [[Category: Polymorphism]] | ||
| + | [[Category: Proteasome]] | ||
| + | [[Category: Protein binding]] | ||
| + | [[Category: PSI, Protein structure initiative]] | ||
Current revision
Crystal Structure of a domain of 26S proteasome regulatory subunit 8 from homo sapiens. Northeast Structural Genomics Consortium target id HR3102A
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Categories: Human | Acton, T B | Baran, M C | Cunningham, K | Hunt, J F | Janjua, H | Liu, J | Montelione, G T | Structural genomic | Owens, L | Seetharaman, J | Su, M | Tong, L | Wang, D | Xiao, R | Acetylation | Atp-binding | Cytoplasm | Nesg | Nucleotide-binding | Nucleus | Polymorphism | Proteasome | Protein binding | PSI, Protein structure initiative
