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From Proteopedia
(Difference between revisions)
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/STK10_HUMAN STK10_HUMAN]] Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.<ref>PMID:11903060</ref> <ref>PMID:12639966</ref> <ref>PMID:19255442</ref> | [[http://www.uniprot.org/uniprot/STK10_HUMAN STK10_HUMAN]] Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.<ref>PMID:11903060</ref> <ref>PMID:12639966</ref> <ref>PMID:19255442</ref> | ||
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| - | ==See Also== | ||
| - | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
[[Category: Canning, P]] | [[Category: Canning, P]] | ||
| - | [[Category: Delft, F | + | [[Category: Delft, F von]] |
[[Category: Edwards, A]] | [[Category: Edwards, A]] | ||
[[Category: Elkins, J M]] | [[Category: Elkins, J M]] | ||
Revision as of 19:45, 24 January 2018
Crystal Structure of Human Serine Threonine Kinase-10 (LOK) Bound to GW830263A
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Categories: Human | Non-specific serine/threonine protein kinase | Arrowsmith, C | Bountra, C | Canning, P | Delft, F von | Edwards, A | Elkins, J M | Knapp, S | Liu, Y | Salah, E | Szklarz, M | Yue, W | Lok | Stk10 | Transferase
