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4w9w

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<StructureSection load='4w9w' size='340' side='right' caption='[[4w9w]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
<StructureSection load='4w9w' size='340' side='right' caption='[[4w9w]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4w9w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W9W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4w9w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W9W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W9W FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=YDJ:5-(3-FLUOROPHENYL)-N-[(3S)-3-PIPERIDYL]-3-UREIDO-THIOPHENE-2-CARBOXAMIDE'>YDJ</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=YDJ:5-(3-FLUOROPHENYL)-N-[(3S)-3-PIPERIDYL]-3-UREIDO-THIOPHENE-2-CARBOXAMIDE'>YDJ</scene></td></tr>
 +
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BMP2K, BIKE, HRIHFB2017 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w9w OCA], [http://pdbe.org/4w9w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4w9w RCSB], [http://www.ebi.ac.uk/pdbsum/4w9w PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w9w OCA], [http://pdbe.org/4w9w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4w9w RCSB], [http://www.ebi.ac.uk/pdbsum/4w9w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4w9w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Bountra, C]]
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[[Category: Delft, F Von]]
+
[[Category: Delft, F von]]
[[Category: Edwards, A M]]
[[Category: Edwards, A M]]
[[Category: Elkins, J M]]
[[Category: Elkins, J M]]

Revision as of 20:23, 24 January 2018

Crystal Structure of BMP-2-inducible kinase in complex with small molecule AZD-7762

4w9w, resolution 1.72Å

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