2dw2
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 2dw2 |SIZE=350|CAPTION= <scene name='initialview01'>2dw2</scene>, resolution 2.7Å | |PDB= 2dw2 |SIZE=350|CAPTION= <scene name='initialview01'>2dw2</scene>, resolution 2.7Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[2dw0|2DW0]], [[2dw1|2DW1]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dw2 OCA], [http://www.ebi.ac.uk/pdbsum/2dw2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2dw2 RCSB]</span> | ||
}} | }} | ||
| Line 25: | Line 28: | ||
[[Category: Igarashi, T.]] | [[Category: Igarashi, T.]] | ||
[[Category: Takeda, S.]] | [[Category: Takeda, S.]] | ||
| - | [[Category: CA]] | ||
| - | [[Category: ZN]] | ||
[[Category: apoptotic toxin]] | [[Category: apoptotic toxin]] | ||
[[Category: metalloproteinase]] | [[Category: metalloproteinase]] | ||
[[Category: svmp]] | [[Category: svmp]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:40:20 2008'' |
Revision as of 23:40, 30 March 2008
| |||||||
| , resolution 2.7Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , , , , | ||||||
| Related: | 2DW0, 2DW1
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of VAP2 from Crotalus atrox venom (Form 2-5 crystal)
Overview
Catrocollastatin/vascular apoptosis-inducing protein (VAP)2B is a metalloproteinase from Crotalus atrox venom, possessing metalloproteinase/disintegrin/cysteine-rich (MDC) domains that bear the typical domain architecture of a disintegrin and metalloproteinase (ADAM)/adamalysin/reprolysin family proteins. Here we describe crystal structures of catrocollastatin/VAP2B in three different crystal forms, representing the first reported crystal structures of a member of the monomeric class of this family of proteins. The overall structures show good agreement with both monomers of atypical homodimeric VAP1. Comparison of the six catrocollastatin/VAP2B monomer structures and the structures of VAP1 reveals a dynamic, modular architecture that may be important for the functions of ADAM/adamalysin/reprolysin family proteins.
About this Structure
2DW2 is a Single protein structure of sequence from Crotalus atrox. Full crystallographic information is available from OCA.
Reference
Crystal structures of catrocollastatin/VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/reprolysin family proteins., Igarashi T, Araki S, Mori H, Takeda S, FEBS Lett. 2007 May 29;581(13):2416-22. Epub 2007 Apr 30. PMID:17485084
Page seeded by OCA on Mon Mar 31 02:40:20 2008
