This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Sandbox Reserved 1442
From Proteopedia
(New page: {{Sandbox_MedChem-StOlaf_Hanson}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> ==Your Heading Here (maybe something like 'Structure')== <StructureSection load='1stp' size='340' side='right' ...) |
|||
| Line 1: | Line 1: | ||
| - | + | ==Crystal structure of the µ-opioid receptor bound to a morphinan antagonist== | |
| - | == | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | == Function == | ||
| - | + | [https://www.nature.com/articles/nature10954 Nature volume 485, pages 321–326 (17 May 2012) | |
| + | doi:10.1038/nature10954] | ||
| - | == | + | <StructureSection load='http://proteopedia.org/wiki/images/a/a6/Animation1.png' size='340' side='right' caption='Click a green link on the left to load Figure 1' scene=''> |
| - | == | + | <jmol><jmollink><text>View Figure 1a: Overall view of the µ-OR structure</text><script>exit;figure=1;SCRIPT "/wiki/images/8/8b/4dkl-local-contact.png"</script></jmollink></jmol> |
| + | |||
| + | Shown in Figure 1a is a close-up view of a morphinan antagonist ([https://chemapps.stolaf.edu/jmol/jmol.php?pdbid=BF0&script=set%20echo%20top%20left;echo%20PDBid%20BF0;spin%20on PDBid BF0]) bound to the µ-opioid receptor. The green circles indicate hydrogen bonds. | ||
| + | |||
| + | <jmol><jmollink><text>Animate Figure 1a</text><script>script "http://proteopedia.org/wiki/images/1/1f/Nature10954_fig1a.spt"</script></jmollink></jmol> | ||
| - | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
</StructureSection> | </StructureSection> | ||
| - | = | + | |
| + | |||
| + | code for the above (space inserted just after the : <code><jmol><jmollink><text>View Figure 1a: Overall view of the µ-OR structure</text><script>exit;figure=1;SCRIPT "/wiki/images/8/8b/4dkl-local-contact.png"</script></jmollink></jmol></code> | ||
| + | |||
| + | |||
<references/> | <references/> | ||
Revision as of 17:40, 29 January 2018
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
[https://www.nature.com/articles/nature10954 Nature volume 485, pages 321–326 (17 May 2012) doi:10.1038/nature10954]
| |||||||||||
code for the above (space inserted just after the : <jmol><jmollink><text>View Figure 1a: Overall view of the µ-OR structure</text><script>exit;figure=1;SCRIPT "/wiki/images/8/8b/4dkl-local-contact.png"</script></jmollink></jmol>
