This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6bdt
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Human Calpain-3 Protease Core Mutant-C129S== | |
| - | + | <StructureSection load='6bdt' size='340' side='right' caption='[[6bdt]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bdt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BDT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BDT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calpain-3 Calpain-3], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.54 3.4.22.54] </span></td></tr> |
| - | [[Category: Davies, P | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bdt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bdt OCA], [http://pdbe.org/6bdt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bdt RCSB], [http://www.ebi.ac.uk/pdbsum/6bdt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bdt ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Autosomal recessive limb girdle muscular dystrophy type 2A. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Calcium-regulated non-lysosomal thiol-protease. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Calpain-3]] | ||
| + | [[Category: Campbell, R L]] | ||
| + | [[Category: Davies, P L]] | ||
[[Category: Ye, Q]] | [[Category: Ye, Q]] | ||
| - | [[Category: | + | [[Category: Calcium binding]] |
| + | [[Category: Calpain]] | ||
| + | [[Category: Cysteine protease]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: P94]] | ||
Revision as of 06:19, 7 February 2018
Crystal Structure of Human Calpain-3 Protease Core Mutant-C129S
| |||||||||||
Categories: Calpain-3 | Campbell, R L | Davies, P L | Ye, Q | Calcium binding | Calpain | Cysteine protease | Hydrolase | P94
